First-in-humans study of the safety, tolerability, and pharmacokinetics of ACT-451840, a new chemical entity with antimalarial activity (Q35105980)

6 August 2017

First-in-humans study of the safety, tolerability, and pharmacokinetics of ACT-451840, a new chemical entity with antimalarial activity (English)

1 reference

6 August 2017

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421475%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Shirin Bruderer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421475%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Noémie Hurst

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421475%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Tommaso Miraval

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421475%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Thomas Pfeifer

5

1 reference

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9 June 2020

Yves Donazzolo

6

1 reference

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9 June 2020

Jasper Dingemanse

7

1 reference

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9 June 2020

language of work or name

English

0 references

publication date

24 November 2014

1 reference

Antimicrobial Agents and Chemotherapy

6 August 2017

8

1 reference

based on heuristic

inferred from page(s)

published in

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9 June 2020

volume

59

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9 June 2020

issue

2

1 reference

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9 June 2020

page(s)

935-942

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421475%20AND%20SRC:MED&resulttype=core&format=json

The changing risk of Plasmodium falciparum malaria infection in Africa: 2000-10: a spatial and temporal analysis of transmission intensity

9 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Identification of a new chemical class of antimalarials

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Artemisone uptake in Plasmodium falciparum-infected erythrocytes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Thousands of chemical starting points for antimalarial lead identification

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Understanding the pharmacokinetics of Coartem

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Plasmodium falciparum-based bioassay for measurement of artemisinin derivatives in plasma or serum

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Carrier-mediated partitioning of artemisinin into Plasmodium falciparum-infected erythrocytes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Confidence interval criteria for assessment of dose proportionality.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

The effects of food on drug bioavailability

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Formulation design and in vivo antimalarial evaluation of lipid-based drug delivery systems for oral delivery of β-arteether.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Influence of bile on the absorption of halofantrine from lipid-based formulations.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

How much fat is necessary to optimize lumefantrine oral bioavailability?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335896

Determination of mean valproic acid serum level by assay of a single pooled sample

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25421475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

On the mechanism for the red-cell accumulation of mefloquine, an antimalarial drug

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25421475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.04125-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421475%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421475%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference