Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases (Q35107180)

6 August 2017

title

Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases (English)

1 reference

6 August 2017

B P Atanasov

1

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6 August 2017

D Mustafi

series ordinal

2

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6 August 2017

M W Makinen

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

1 March 2000

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6 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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6 August 2017

volume

97

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6 August 2017

issue

7

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6 August 2017

page(s)

3160-3165

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A self-consistent, microenvironment modulated screened coulomb potential approximation to calculate pH-dependent electrostatic effects in proteins

6 August 2017

cites work

1 reference

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pKa calculations for class A beta-lactamases: influence of substrate binding

9 July 2018

1 reference

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Crystal structure of an acylation transition-state analog of the TEM-1 beta-lactamase. Mechanistic implications for class A beta-lactamases

9 July 2018

1 reference

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pKa calculations for class A beta-lactamases: methodological and mechanistic implications

9 July 2018

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Crystal structure of the wide-spectrum binuclear zinc beta-lactamase from Bacteroides fragilis

9 July 2018

1 reference

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The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme

9 July 2018

1 reference

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Inhibition and catalytic mechanism of HIV-1 aspartic protease

9 July 2018

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Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution

9 July 2018

1 reference

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Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis

9 July 2018

1 reference

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Molecular structures of penicillin-binding proteins and beta-lactamases

9 July 2018

1 reference

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Substitution of Asp for Asn at position 132 in the active site of TEM beta-lactamase. Activity toward different substrates and effects of neighboring residues

9 July 2018

1 reference

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The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold

9 July 2018

1 reference

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Calculations of electrostatic interactions in biological systems and in solutions

9 July 2018

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The interpretation of protein structures: Estimation of static accessibility

9 July 2018

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The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family

9 July 2018

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Evidence for an oxyanion hole in serine beta-lactamases and DD-peptidases

9 July 2018

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How do serine proteases really work?

9 July 2018

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Electrostatic interactions in macromolecules: theory and applications

9 July 2018

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The role of lysine-234 in beta-lactamase catalysis probed by site-directed mutagenesis

9 July 2018

1 reference

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Electrostatic Energy and Macromolecular Function

9 July 2018

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The crisis in antibiotic resistance

9 July 2018

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Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

9 July 2018

1 reference

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The pH-dependence and group modification of β-lactamase I

9 July 2018

1 reference

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A new TEM beta-lactamase double mutant with broadened specificity reveals substrate-dependent functional interactions.

9 July 2018

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CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

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Comparison of simple potential functions for simulating liquid water

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.97.7.3160

Electrostatic analysis of TEM1 β-lactamase: effect of substrate binding, steep potential gradients and consequences of site-directed mutations

21 January 2018

1 reference

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pH dependence and solvent deuterium oxide kinetic isotope effects on Bacillus cereus beta-lactamase I catalyzed reactions

21 January 2018

1 reference

12 December 2020

Site-directed mutants, at position 166, of RTEM-1 beta-lactamase that form a stable acyl-enzyme intermediate with penicillin

1 reference

12 December 2020

Modeling study on a hydrolytic mechanism of class A beta-lactamases

1 reference

12 December 2020

Structure-based design of a potent transition state analogue for TEM-1 beta-lactamase

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12 December 2020

Molecular evolution of bacterial beta-lactam resistance

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12 December 2020

Site-directed mutagenesis of glutamate 166 in two beta-lactamases. Kinetic and molecular modeling studies

1 reference

12 December 2020

Local electrostatic potentials in pyridoxal phosphate labelled horse heart cytochrome c

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12 December 2020

Identifiers

DOI

10.1073/PNAS.97.7.3160

1 reference

release_if7aybwu6ng6rdub2zeqkrykcm

6 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/if7aybwu6ng6rdub2zeqkrykcm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

16209

1 reference

6 August 2017

1 reference