Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors (Q35110055)

6 August 2017

Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors (English)

1 reference

3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE

6 August 2017

0 references

1 reference

ChEBI release 2020-05-28

ChEBI ID

44612

Staphylococcus aureus

1 reference

Paul O'Shea

8

0 references

Weng C. Chan

object named as

Weng C Chan

12

0 references

Paul Williams

object named as

Paul Williams

13

0 references

author name string

Ewan J Murray

1

1 reference

6 August 2017

Rebecca C Crowley

2

1 reference

6 August 2017

Alex Truman

3

1 reference

6 August 2017

Simon R Clarke

4

1 reference

6 August 2017

James A Cottam

5

1 reference

6 August 2017

Gopal P Jadhav

6

1 reference

6 August 2017

Victoria R Steele

7

1 reference

6 August 2017

Catharina Lindholm

9

1 reference

6 August 2017

Alan Cockayne

10

1 reference

6 August 2017

Siri Ram Chhabra

11

1 reference

6 August 2017

language of work or name

English

0 references

publication date

13 March 2014

1 reference

Journal of Medicinal Chemistry

6 August 2017

1 reference

6 August 2017

57

1 reference

6 August 2017

6

1 reference

6 August 2017

2813-2819

1 reference

Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing.

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

The Fe(III) and Ga(III) coordination chemistry of 3-(1-hydroxymethylidene) and 3-(1-hydroxydecylidene)-5-(2-hydroxyethyl)pyrrolidine-2,4-dione: novel tetramic acid degradation products of homoserine lactone bacterial quorum sensing molecules

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

The interaction of N-acylhomoserine lactone quorum sensing signaling molecules with biological membranes: implications for inter-kingdom signaling

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Anti-Clostridium difficile potential of tetramic acid derivatives from Pseudomonas aeruginosa quorum-sensing autoinducers

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Symmetric signalling within asymmetric dimers of the Staphylococcus aureus receptor histidine kinase AgrC

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Meldrum's acid and related compounds in the synthesis of natural products and analogs

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Tetramic and tetronic acids: an update on new derivatives and biological aspects

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Targeting virulence: a new paradigm for antimicrobial therapy

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Look who's talking: communication and quorum sensing in the bacterial world.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Iron and microbial infection

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Staphylococcus aureus clumping factor B (ClfB) promotes adherence to human type I cytokeratin 10: implications for nasal colonization

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Highly potent inhibitors of quorum sensing in Staphylococcus aureus revealed through a systematic synthetic study of the group-III autoinducing peptide

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Roles of Pseudomonas aeruginosa autoinducers and their degradation products, tetramic acids, in bacterial survival and behavior in ecological niches.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

N-acylhomoserine lactones antagonize virulence gene expression and quorum sensing in Staphylococcus aureus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Structure, activity and evolution of the group I thiolactone peptide quorum-sensing system of Staphylococcus aureus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010551

Autoregulation of carbapenem biosynthesis in Erwinia carotovora by analogues of N-(3-oxohexanoyl)-L-homoserine lactone

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24592914

12 December 2020

inferred from PubMed ID database lookup

Immunosuppressive but non-LasR-inducing analogues of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-l-homoserine lactone

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24592914

12 December 2020

inferred from PubMed ID database lookup

Formylated peptides are important virulence factors in Staphylococcus aureus arthritis in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24592914

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1021/JM500215S

1 reference

release_nz5q5yg5gzhrrbraiu2m2nfwcm

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nz5q5yg5gzhrrbraiu2m2nfwcm

24 November 2022

mapped directly with Wikidata item

PMCID

4010551

1 reference

6 August 2017

1 reference