Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide (Q35110170)

24593254

6 August 2017

title

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide (English)

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6 August 2017

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8 June 2020

Lucia Ricci Vitiani

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8 June 2020

Fabio Ciccarone

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8 June 2020

Roberto Pallini

8

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8 June 2020

Grazia Graziani

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8 June 2020

3

Alessia Muzi

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8 June 2020

author name string

Federica Pelacchi

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8 June 2020

Roberta Calabrese

6

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8 June 2020

Daniele Runci

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8 June 2020

Paola Caiafa

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8 June 2020

language of work or name

English

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publication date

5 March 2014

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6 August 2017

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8 June 2020

volume

14

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8 June 2020

page(s)

151

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MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.

8 June 2020

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Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients

9 July 2018

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A distinct region of the MGMT CpG island critical for transcriptional regulation is preferentially methylated in glioblastoma cells and xenografts.

9 July 2018

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PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.

9 July 2018

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Gene expression profiling predicts response to temozolomide in malignant gliomas

9 July 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

9 July 2018

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9 July 2018

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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

9 July 2018

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Acquired resistance to combination treatment with temozolomide and ABT-888 is mediated by both base excision repair and homologous recombination DNA repair pathways

9 July 2018

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

9 July 2018

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Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas

9 July 2018

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Recent approaches to improve the antitumor efficacy of temozolomide.

9 July 2018

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In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.

9 July 2018

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Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

9 July 2018

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Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant glioma

9 July 2018

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9 July 2018

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9 July 2018

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

9 July 2018

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The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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21 January 2018

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Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.

21 January 2018

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Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.

21 January 2018

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Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma

27 September 2018

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Involvement of the mismatch repair system in temozolomide-induced apoptosis

27 September 2018

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Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

27 September 2018

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Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24593254

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12 December 2020

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Identifiers

DOI

10.1186/1471-2407-14-151

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8 June 2020

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8 June 2020

24593254

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