Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke. (Q35117578)

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English	Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.	scientific article

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1 March 2020

Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke (English)

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Tiina M. Kauppinen

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Midori A Yenari

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Masahito Kawabori

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Rachid Kacimi

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Cyrus Calosing

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Jong Youl Kim

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Christine L Hsieh

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Mary C Nakamura

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1 February 2015

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Journal of Neuroscience

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35

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3384-3396

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11 June 2022

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Phagocytosis of microglia in the central nervous system diseases

1 reference

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9 July 2018

Triggering Receptor Expressed on Myeloid Cells-2 Correlates to Hypothermic Neuroprotection in Ischemic Stroke

1 reference

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Microglial P2Y12 deficiency/inhibition protects against brain ischemia

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Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke

1 reference

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Variant of TREM2 Associated with the Risk of Alzheimer's Disease

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Novel therapeutic strategies targeting innate immune responses and early inflammation after stroke

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Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke.

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The immunology of stroke: from mechanisms to translation

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Microglial activation in stroke: therapeutic targets

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The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor

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A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

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The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12

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Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke

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TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis

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Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

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Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia

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Pattern recognition by TREM-2: binding of anionic ligands

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TREMs in the immune system and beyond

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Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia

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12 December 2020

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10.1523/JNEUROSCI.2620-14.2015

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1 March 2020

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