The Ketogenic Diet for the Treatment of Epilepsy: A Challenge for Nutritional Neuroscientists (Q35117887)

6 August 2017

1 reference

title

The ketogenic diet for the treatment of epilepsy: a challenge for nutritional neuroscientists (English)

1 reference

6 August 2017

The Ketogenic Diet for the Treatment of Epilepsy: A Challenge for Nutritional Neuroscientists (English)

1 reference

https://api.crossref.org/works/10.1080/1028415031000084427

29 December 2023

1

Carl E. Stafstrom

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12722982

29 December 2023

author name string

Kristopher J. Bough

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12722982

29 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12722982

29 December 2023

publication date

1 April 2003

1 reference

full work available at URL

6 August 2017

http://www.tandfonline.com/doi/pdf/10.1080/1028415031000084427

1 reference

https://api.crossref.org/works/10.1080/1028415031000084427

29 December 2023

published in

Nutritional Neuroscience

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6 August 2017

6

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6 August 2017

2

1 reference

6 August 2017

67-79

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Diet-induced ketosis does not cause cerebral acidosis.

6 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

An animal model for the ketogenic diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Effect of ketone body (d-3-hydroxybutyrate) on neural activity and energy metabolism in hippocampal slices of the adult guinea pig

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Glucose transporter type 1 deficiency: a study of two cases with video-EEG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Comparison of the anticonvulsant efficacies and neurotoxic effects of valproic acid, phenytoin, and the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet in children, adolescents and young adults with refractory epilepsy: an Italian multicentric experience.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Molecular cloning of rat mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase and detection of the corresponding mRNA and of those encoding the remaining enzymes comprising the ketogenic 3-hydroxy-3-methylglutaryl-CoA cycle in central nervous system o

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet upregulates expression of the gene encoding the key ketogenic enzyme mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The Activity of D-β-Hydroxybutyrate Dehydrogenase in Fetal, Infant and Adult Rat Brain and the Influence of Starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Lipid and fatty acid profiles in rats consuming different high-fat ketogenic diets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Starvation and seizures. Observation on the electroconvulsive threshold and cerebral metabolism of the starved adult rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Chronic ketosis and cerebral metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Defective Glucose Transport across the Blood-Brain Barrier as a Cause of Persistent Hypoglycorrhachia, Seizures, and Developmental Delay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Management of seizure disorders: selected aspects. Part II

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Seizures decrease rapidly after fasting: preliminary studies of the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Risk factors for urolithiasis in children on the ketogenic diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet: seizure control correlates better with serum beta-hydroxybutyrate than with urine ketones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Glucose treatment reduces memory deficits in young adult rats fed high-fat diets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Effects of acute inhibition of fatty acid oxidation on latency to seizure and concentrations of beta hydroxybutyrate in plasma of rats maintained on calorie restriction and/or the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketone-body utilization by adult and suckling rat brain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketogenic diet: effects on expression of kindled seizures and behavior in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Medium‐chain triglycerides as a therapy for intractable childhood epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

beta-Hydroxybutyrate fuels synaptic function during development. Histological and physiological evidence in rat hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Efficacy of the ketogenic diet for intractable seizure disorders: review of 58 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Facilitated glucose transporter protein type 1 (GLUT1) deficiency syndrome: impaired glucose transport into brain-- a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Efficacy of the ketogenic diet for infantile spasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Functional and electrophysiologic effects of polyunsaturated fatty acids on exictable tissues: heart and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Diet-induced ketosis increases monocarboxylate transporter (MCT1) levels in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Regulation of hepatic fatty acid oxidation and ketone body production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketogenic diet reduces spontaneous seizures and mossy fiber sprouting in the kainic acid model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Epilepsy and the ketogenic diet: assessment of ketosis in children using breath acetone

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet revisited: back to the future.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Experience with the ketogenic diet in infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Brain Metabolism during Fasting*

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketosis and epilepsy: 31P spectroscopic imaging at 4.1 T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Human brain beta-hydroxybutyrate and lactate increase in fasting-induced ketosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Measurement of beta-hydroxybutyrate in acute hyperketonemia in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Developmental seizure susceptibility of kv1.1 potassium channel knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Metabolic and endocrine aspects of the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The metabolic events of starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Mechanisms underlying the anti-epileptic efficacy of the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet for intractable epilepsy in adults: preliminary results

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Oxidative stress, caloric restriction, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Metabolism of Ketone Bodies by the Brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Animal models of the ketogenic diet: what have we learned, what can we learn?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Timing of ketogenic diet initiation in an experimental epilepsy model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Norepinephrine is required for the anticonvulsant effect of the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Role of essential fatty acids in the function of the developing nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

A multicenter study of the efficacy of the ketogenic diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Clinical efficacy of the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The effects of lactate and beta-hydroxybutyrate on the energy metabolism and neural activity of hippocampal slices from adult and immature rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Outcome of pyruvate dehydrogenase deficiency treated with ketogenic diets. Studies in patients with identical mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet: an effective medical therapy with side effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Vagus nerve stimulation and the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Clinical significance of animal seizure models and mechanism of action studies of potential antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Leigh syndrome associated with a deficiency of the pyruvate dehydrogenase complex: results of treatment with a ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Growth retardation in children with epilepsy on the ketogenic diet: a retrospective chart review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Is a fast necessary when initiating the ketogenic diet?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Brain amino acid metabolism and ketosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketogenic diet, amino acid metabolism, and seizure control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency: clinical course and description of causal mutations in two patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Higher ketogenic diet ratios confer protection from seizures without neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Growth and nutritional outcomes of children treated with the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Plasma lipids in epileptic children treated with the high fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet in refractory epilepsy: the experience of Children's Hospital of Pittsburgh

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Developmental changes of cerebral ketone body utilization in human infants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Dietary practices and use of the ketogenic diet in the UK

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Medical costs are reduced when children with intractable epilepsy are successfully treated with the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Efficacy of the ketogenic diet in focal versus generalized seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Age-dependent pathways of brain energy metabolism: the suckling rat, a natural model of the ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Effects of ketogenic diet on development and behavior: preliminary report of a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

21 January 2018

The new health care game

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Metabolic effects of three ketogenic diets in the treatment of severe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Ketogenic diets in the treatment of epilepsy: short-term clinical effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet: a therapy in search of an explanation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The MCT ketogenic diet: effects on animal seizure models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

The ketogenic diet: Fa(c)t or fiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F1028415031000084427

Regulation of GABA level in rat brain synaptosomes: fluxes through enzymes of the GABA shunt and effects of glutamate, calcium, and ketone bodies.

21 January 2018

24

1 reference

https://api.crossref.org/works/10.1080/1028415031000084427

29 December 2023

Medical Science Monitor

50

8

HY19

Likhodhii S.S.

2002

1 reference

https://api.crossref.org/works/10.1080/1028415031000084427

Beta-hydroxybutyrate transport in rat brain: developmental and dietary modulations

29 December 2023

60

1 reference

https://api.crossref.org/works/10.1080/1028415031000084427

Physiological roles of ketone bodies as substrates and signals in mammalian tissues

29 December 2023

80

1 reference

https://api.crossref.org/works/10.1080/1028415031000084427

29 December 2023

114

2

307

Wilder R.M.

1921

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https://api.crossref.org/works/10.1080/1028415031000084427

29 December 2023

Identifiers

1 reference

6 August 2017

1 reference