Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer (Q35118166)

6 August 2017

title

Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer (English)

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6 August 2017

1

Lyndsay V Rhodes

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6 August 2017

24

Paul Dent

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28

Ann Richmond

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23

Kenneth P Nephew

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6 August 2017

Dihua Yu

8

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ORCID Public Data File 2021

Mien-Chie Hung

27

object named as

Mien-Chie Hung

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6 August 2017

7

Yongkun Wei

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6 August 2017

Sarah P Short

2

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6 August 2017

Nicole F Neel

3

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Virgilio A Salvo

4

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6 August 2017

Yun Zhu

5

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6 August 2017

Steven Elliott

6

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6 August 2017

Menghong Sun

9

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6 August 2017

Shannon E Muir

10

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6 August 2017

Juan P Fonseca

11

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6 August 2017

Melyssa R Bratton

12

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6 August 2017

Chris Segar

13

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6 August 2017

Syreeta L Tilghman

14

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6 August 2017

Tammy Sobolik-Delmaire

15

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6 August 2017

Linda W Horton

16

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6 August 2017

Snjezana Zaja-Milatovic

17

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6 August 2017

Bridgette M Collins-Burow

18

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6 August 2017

Scott Wadsworth

19

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6 August 2017

Barbara S Beckman

20

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6 August 2017

Charles E Wood

21

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6 August 2017

Suzanne A Fuqua

22

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6 August 2017

Rebecca A Worthylake

25

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6 August 2017

Tyler J Curiel

26

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6 August 2017

Matthew E Burow

29

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6 August 2017

language of work or name

English

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publication date

1 December 2010

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6 August 2017

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6 August 2017

volume

71

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6 August 2017

issue

2

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6 August 2017

page(s)

603-613

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Challenges in defining predictive markers for response to endocrine therapy in breast cancer

6 August 2017

cites work

1 reference

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9 July 2018

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Biological determinants of endocrine resistance in breast cancer

9 July 2018

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Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways.

9 July 2018

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Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence.

9 July 2018

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Positive feedback activation of estrogen receptors by the CXCL12-CXCR4 pathway

9 July 2018

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A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer

9 July 2018

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CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.

9 July 2018

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CXCR4 receptor positive spheroid forming cells are responsible for tumor invasion in vitro

9 July 2018

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9 July 2018

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Relevance of breast cancer antiestrogen resistance genes in human breast cancer progression and tamoxifen resistance

9 July 2018

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Regulation of cell-cell adhesion by the cadherin-catenin complex

9 July 2018

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17beta-estradiol promotes breast cancer cell proliferation-inducing stromal cell-derived factor-1-mediated epidermal growth factor receptor transactivation: reversal by gefitinib pretreatment

9 July 2018

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The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha

9 July 2018

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Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling

9 July 2018

1 reference

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Akt plays an important role in breast cancer cell chemotaxis to CXCL12.

9 July 2018

1 reference

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CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway

9 July 2018

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Antiestrogenic glyceollins suppress human breast and ovarian carcinoma tumorigenesis

9 July 2018

1 reference

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Stromal fibroblasts in cancer: a novel tumor-promoting cell type

9 July 2018

1 reference

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Deletion of the COOH-terminal domain of CXC chemokine receptor 4 leads to the down-regulation of cell-to-cell contact, enhanced motility and proliferation in breast carcinoma cells

9 July 2018

1 reference

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The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study.

9 July 2018

1 reference

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Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

9 July 2018

1 reference

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CXCR4 regulates growth of both primary and metastatic breast cancer

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma

9 July 2018

1 reference

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Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation

9 July 2018

1 reference

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Involvement of chemokine receptors in breast cancer metastasis

9 July 2018

1 reference

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Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

9 July 2018

1 reference

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Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods

9 July 2018

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Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants.

9 July 2018

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Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4.

9 July 2018

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Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation

9 July 2018

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9 July 2018

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The invasive and metastatic properties of hormone-independent but hormone-responsive variants of MCF-7 human breast cancer cells.

9 July 2018

1 reference

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Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

SDF-1alpha/CXCR4 decreases endothelial progenitor cells apoptosis under serum deprivation by PI3K/Akt/eNOS pathway

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Elevated chemokine receptor CXCR4 expression in primary tumors following neoadjuvant chemotherapy predicts poor outcomes for patients with locally advanced breast cancer (LABC).

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Effect of levonorgestrel IUD and oral medroxyprogesterone acetate on glandular and stromal progesterone receptors (PRA and PRB), and estrogen receptors (ER-alpha and ER-beta) in human endometrial hyperplasia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3140407

Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice

27 September 2018

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12 December 2020

Immune-deficient animals to study "hormone-dependent" breast and endometrial cancer

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12 December 2020

[Prognostic value of lympho node micrometastases detected by immunohistochemistry. Study of 168 cases of breast cancer with a 10-year follow-up]

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12 December 2020

Estrogen receptor phosphorylation. Hormonal dependence and consequence on specific DNA binding

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12 December 2020

MCF-7 human breast carcinomas in nude mice as a model for evaluating aromatase inhibitors

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12 December 2020

Immunohistochemical assay for oestrogen receptors in paraffin wax sections of breast carcinoma using a new monoclonal antibody

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12 December 2020

Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas

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12 December 2020

10.1158/0008-5472.CAN-10-3185

Identifiers

DOI

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6 August 2017

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6 August 2017

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