The circadian clock: pacemaker and tumour suppressor (Q35118733)

6 August 2017

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title

The circadian clock: pacemaker and tumour suppressor (English)

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6 August 2017

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Loning Fu

1

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6 August 2017

Cheng Chi Lee

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

1 May 2003

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full work available at URL

6 August 2017

https://www.nature.com/articles/nrc1072

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https://www.nature.com/articles/nrc1072.pdf

29 December 2023

file format

Portable Document Format

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29 December 2023

published in

Nature Reviews Cancer

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6 August 2017

3

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6 August 2017

5

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6 August 2017

350-361

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https://scigraph.springernature.com/pub.10.1038/nrc1072

6 August 2017

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cites work

ON TEMPERATURE INDEPENDENCE IN THE CLOCK SYSTEM CONTROLLING EMERGENCE TIME IN DROSOPHILA

1 reference

Circadian systems. I. The driving oscillation and its assay in Drosophila pseudoobscura

31 March 2020

1 reference

Restoration of circadian behavioural rhythms by gene transfer in Drosophila

31 March 2020

1 reference

Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms

31 March 2020

1 reference

Time zones: a comparative genetics of circadian clocks

31 March 2020

1 reference

Circadian-system alterations during cancer processes: a review

31 March 2020

1 reference

Rotating night shifts and risk of breast cancer in women participating in the nurses' health study

31 March 2020

1 reference

Increased breast cancer risk among women who work predominantly at night

31 March 2020

1 reference

The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo

31 March 2020

1 reference

Host circadian clock as a control point in tumor progression.

31 March 2020

1 reference

From circadian rhythms to cancer chronotherapeutics

31 March 2020

1 reference

Positional cloning of the mouse circadian clock gene

31 March 2020

1 reference

A Mutation of the Circadian System in Golden Hamsters

31 March 2020

1 reference

Cloning and characterization of rat casein kinase 1epsilon

31 March 2020

1 reference

Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins

31 March 2020

1 reference

Cloning, tissue expression, and mapping of a human photolyase homolog with similarity to plant blue-light receptors

31 March 2020

1 reference

Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses.

31 March 2020

1 reference

Circadian oscillation of a mammalian homologue of the Drosophila period gene

31 March 2020

1 reference

RIGUI, a putative mammalian ortholog of the Drosophila period gene

31 March 2020

1 reference

Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei.

31 March 2020

1 reference

A light-independent oscillatory gene mPer3 in mouse SCN and OVLT.

31 March 2020

1 reference

A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light.

31 March 2020

1 reference

The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors

31 March 2020

1 reference

Circadian oscillation of BMAL1, a partner of a mammalian clock gene Clock, in rat suprachiasmatic nucleus

31 March 2020

1 reference

Molecular analysis of mammalian circadian rhythms

31 March 2020

1 reference

Coordination of circadian timing in mammals

31 March 2020

1 reference

Circadian rhythms from flies to human

31 March 2020

1 reference

Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat.

31 March 2020

1 reference

Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions

31 March 2020

1 reference

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

31 March 2020

1 reference

Cellular construction of a circadian clock: period determination in the suprachiasmatic nuclei.

31 March 2020

1 reference

Absence of circadian phase resetting in response to bright light behind the knees

31 March 2020

1 reference

Identifying the photoreceptive inputs to the mammalian circadian system using transgenic and retinally degenerate mice.

31 March 2020

1 reference

Regulation of mammalian circadian behavior by non-rod, non-cone, ocular photoreceptors.

31 March 2020

1 reference

Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors.

31 March 2020

1 reference

Suppression of melatonin secretion in some blind patients by exposure to bright light

31 March 2020

1 reference

Melanopsin in cells of origin of the retinohypothalamic tract

31 March 2020

1 reference

Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity

31 March 2020

1 reference

Role of melanopsin in circadian responses to light

31 March 2020

1 reference

Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting

31 March 2020

1 reference

Reduced pupillary light responses in mice lacking cryptochromes.

31 March 2020

1 reference

Output pathways of the mammalian suprachiasmatic nucleus: coding circadian time by transmitter selection and specific targeting

31 March 2020

1 reference

Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway

31 March 2020

1 reference

Three period homologs in mammals: differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain.

31 March 2020

1 reference

No circadian rhythms in testis: Period1 expression is clock independent and developmentally regulated in the mouse.

31 March 2020

1 reference

A serum shock induces circadian gene expression in mammalian tissue culture cells

31 March 2020

1 reference

Multitissue circadian expression of rat period homolog (rPer2) mRNA is governed by the mammalian circadian clock, the suprachiasmatic nucleus in the brain

31 March 2020

1 reference

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

31 March 2020

1 reference

Entrainment of the circadian clock in the liver by feeding

31 March 2020

1 reference

Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors

31 March 2020

1 reference

Metabolism and the control of circadian rhythms

31 March 2020

1 reference

Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators

31 March 2020

1 reference

Analysis of circadian liver gene expression by ADDER, a highly sensitive method for the display of differentially expressed mRNAs

31 March 2020

1 reference

Coordinated transcription of key pathways in the mouse by the circadian clock

31 March 2020

1 reference

Circadian programs of transcriptional activation, signaling, and protein turnover revealed by microarray analysis of mammalian cells

31 March 2020

1 reference

Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus.

31 March 2020

1 reference

Implications of circadian gene expression in kidney, liver and the effects of fasting on pharmacogenomic studies

31 March 2020

1 reference

Extensive and divergent circadian gene expression in liver and heart

31 March 2020

1 reference

TRENDS IN PHOTOPHYSIOLOGIC CONCEPTS

31 March 2020

1 reference

Influence of environmental light and melatonin upon mammary tumour induction

31 March 2020

1 reference

Effect of pinealectomy and melatonin on mammary tumor growth in Sprague-Dawley rats under different conditions of lighting

31 March 2020

1 reference

The tumor promoting effect of constant light exposure on diethylnitrosamine-induced hepatocarcinogenesis in rats.

31 March 2020

1 reference

Night shift work, light at night, and risk of breast cancer

31 March 2020

1 reference

Risk of breast cancer in female flight attendants: a population-based study (Iceland).

31 March 2020

1 reference

Influences of light-dark shifting on the immune system, tumor growth and life span of rats, mice and fruit flies as well as on the counteraction of melatonin.

31 March 2020

1 reference

Diurnal cortisol rhythm as a predictor of breast cancer survival

31 March 2020

1 reference

Circadian rhythms and cancer chemotherapy

31 March 2020

1 reference

Chronopharmacokinetics. Current status

31 March 2020

1 reference

Timing of cancer chemotherapy based on circadian variations in tumor tissue blood flow

31 March 2020

1 reference

Circadian rhythm of cell division.

31 March 2020

1 reference

Evidence for an ontogenetic basis for circadian coordination of cancer cell proliferation

31 March 2020

1 reference

Circadian and ultradian cytokinetic rhythms of spontaneous human cancer

31 March 2020

1 reference

Tumor-based rhythms of anticancer efficacy in experimental models.

31 March 2020

1 reference

Increased Tolerance of Leukemic Mice to Arabinosyl Cytosine with Schedule Adjusted to Circadian System

31 March 2020

1 reference

Toward a chronotherapy of neoplasia: Tolerance of treatment depends upon host rhythms

31 March 2020

1 reference

Pharmaco-economic comparative evaluation of combination chronotherapy vs. standard chemotherapy for colorectal cancer

31 March 2020

1 reference

Chronomodulated chemotherapy and irradiation: an idea whose time has come?

31 March 2020

1 reference

Marker rhythms of circadian system function: a study of patients with metastatic colorectal cancer and good performance status.

31 March 2020

1 reference

Circadian time-dependent response of childhood lymphoblastic leukemia to chemotherapy: a long-term follow-up study of survival

31 March 2020

1 reference

Hypothalamic integration of central and peripheral clocks

31 March 2020

1 reference

Modulation of DNA synthesis by muscarinic cholinergic receptors

31 March 2020

1 reference

Circadian rhythm of leucocytes and lymphocytes subsets and its possible correlation with the function of the autonomic nervous system

31 March 2020

1 reference

Ventromedial hypothalamus suppresses splenic lymphocyte activity through sympathetic innervation.

31 March 2020

1 reference

The role of the autonomic nervous system in liver regeneration and apoptosis--recent developments

31 March 2020

1 reference

Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy

31 March 2020

1 reference

Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male mice

31 March 2020

1 reference

Apoptotic action of estrogen

31 March 2020

1 reference

Hormonal aspects of breast cancer. Growth factors, drugs and stromal interactions

31 March 2020

1 reference

Effects of deflazacort and cortisone on cellular proliferation in the rat thymus

31 March 2020

1 reference

Immunomodulation by the autonomic nervous system: therapeutic approach for cancer, collagen diseases, and inflammatory bowel diseases.

31 March 2020

1 reference

Biologic rhythms in the immune system

31 March 2020

1 reference

Cancer immunoediting: from immunosurveillance to tumor escape

31 March 2020

1 reference

Changing the dosing schedule minimizes the disruptive effects of interferon on clock function.

31 March 2020

1 reference

Neuroendocrine aspects of the response to stress

31 March 2020

1 reference

Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones

31 March 2020

1 reference

Circadian variation in the expression of cell-cycle proteins in human oral epithelium

31 March 2020

1 reference

Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases

31 March 2020

1 reference

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

31 March 2020

1 reference

Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon

31 March 2020

1 reference

The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling

31 March 2020

1 reference

WNT signaling and lymphocyte development

31 March 2020

1 reference

beta-catenin signaling and cancer

31 March 2020

1 reference

The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors

31 March 2020

1 reference

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

31 March 2020

1 reference

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

31 March 2020

1 reference

Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

31 March 2020

1 reference

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

31 March 2020

1 reference

A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock

31 March 2020

1 reference

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

31 March 2020

1 reference

Low-dose ultraviolet B rays alter the mRNA expression of the circadian clock genes in cultured human keratinocytes

31 March 2020

1 reference

Protein kinase CK2 interacts with and phosphorylates the Arabidopsis circadian clock-associated 1 protein.

31 March 2020

1 reference

The protein kinase CK2 is involved in regulation of circadian rhythms in Arabidopsis.

31 March 2020

1 reference

Regulation of the Neurospora circadian clock by casein kinase II

31 March 2020

1 reference

A role for casein kinase 2alpha in the Drosophila circadian clock

31 March 2020

1 reference

Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis

31 March 2020

1 reference

Protein kinase CK2: signaling and tumorigenesis in the mammary gland

31 March 2020

1 reference

A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

31 March 2020

1 reference

Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms

31 March 2020

1 reference

Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript.

31 March 2020

1 reference

Compositional changes of AP-1 DNA-binding proteins are regulated by light in a mammalian circadian clock

31 March 2020

1 reference

Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei.

31 March 2020

1 reference

Resetting the biological clock: mediation of nocturnal CREB phosphorylation via light, glutamate, and nitric oxide

31 March 2020

1 reference

Nitric oxide synthase inhibitor blocks light-induced phase shifts of the circadian activity rhythm, but not c-fos expression in the suprachiasmatic nucleus of the Syrian hamster

31 March 2020

1 reference

Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock

31 March 2020

1 reference

Synchronization and phase-resetting by glutamate of an immortalized SCN cell line

31 March 2020

1 reference

Resetting of circadian time in peripheral tissues by glucocorticoid signaling

31 March 2020

1 reference

Regulation of CLOCK and MOP4 by Nuclear Hormone Receptors in the Vasculature

31 March 2020

1 reference

Steroid receptor regulated transcription of specific genes and gene networks

31 March 2020

1 reference

The human and mouse Period1 genes: five well-conserved E-boxes additively contribute to the enhancement of mPer1 transcription.

31 March 2020

1 reference

Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts

31 March 2020

1 reference

A circadian output in Drosophila mediated by neurofibromatosis-1 and Ras/MAPK.

31 March 2020

1 reference

Circadian regulation of cGMP-gated cationic channels of chick retinal cones. Erk MAP Kinase and Ca2+/calmodulin-dependent protein kinase II.

31 March 2020

1 reference

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

31 March 2020

1 reference

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

31 March 2020

1 reference

Signaling pathways for PC12 cell differentiation: making the right connections

31 March 2020

1 reference

31 March 2020

1 reference

The protrusive phase and full development of integrin-dependent adhesions in colon epithelial cells require FAK- and ERK-mediated actin spike formation: deregulation in cancer cells

31 March 2020

1 reference

Deregulation of the signaling pathways controlling urokinase production. Its relationship with the invasive phenotype.

31 March 2020

1 reference

Therapeutics targeting signal transduction for patients with colorectal carcinoma

31 March 2020

1 reference

AP-1 as a regulator of cell life and death

31 March 2020

1 reference

Fos family members induce cell cycle entry by activating cyclin D1.

31 March 2020

1 reference

The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest

31 March 2020

1 reference

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

31 March 2020

1 reference

The circadian system of c-fos deficient mice

31 March 2020

1 reference

Retinoid-induced G1 arrest and differentiation activation are associated with a switch to cyclin-dependent kinase-activating kinase hypophosphorylation of retinoic acid receptor alpha

31 March 2020

1 reference

Peroxisome proliferator-activated receptor gamma reduces the growth rate of pancreatic cancer cells through the reduction of cyclin D1.

31 March 2020

1 reference

Retinoic acid promotes ubiquitination and proteolysis of cyclin D1 during induced tumor cell differentiation

31 March 2020

1 reference

Transcriptional regulation in acute promyelocytic leukemia.

31 March 2020

1 reference

Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1

31 March 2020

1 reference

Cross-talk between glucocorticoid receptor and AP-1.

31 March 2020

1 reference

Glucocorticoids activate somatostatin gene transcription through co-operative interaction with the cyclic AMP signalling pathway

31 March 2020

1 reference

Rapid activation of ERK1/2 mitogen-activated protein kinase by corticosterone in PC12 cells

31 March 2020

1 reference

Glucocorticoids antagonize AP-1 by inhibiting the Activation/phosphorylation of JNK without affecting its subcellular distribution

31 March 2020

1 reference

A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms.

31 March 2020

1 reference

Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain.

31 March 2020

1 reference

The suprachiasmatic nucleus and the circadian time-keeping system revisited

31 March 2020

1 reference

Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release

31 March 2020

1 reference

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

31 March 2020

1 reference

Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

31 March 2020

1 reference

Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock.

31 March 2020

1 reference

An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome

31 March 2020

1 reference

Circadian variation of cell proliferation and cell cycle protein expression in man: clinical implications

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Circadian rhythm of cellular proliferation in the human rectal mucosa

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Light and immunomodulation

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

66

44

3403

PN Shah

1984

1 reference

29 December 2023

Cell and Tissue Kinetics

84

10

313

JN Izquierdo

1977

1 reference

29 December 2023

86

47

6267

RR Klevecz

1987

1 reference

29 December 2023

89

53

3129

R Smaaland

1993

1 reference

29 December 2023

93

49

3362

N Boughattas

1989

1 reference

Journal of Pharmacology and Experimental Therapeutics

29 December 2023

94

283

1383

S Ohdo

1997

1 reference

Control of cell cycle progression by c-Jun is p53 dependent

29 December 2023

series ordinal

171

1 reference

29 December 2023

186

46

2457

SB Eastman-Reks

1986

1 reference

29 December 2023

187

55

4188

K Rhee

1995

1 reference

29 December 2023

Identifiers

DOI

10.1038/NRC1072

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6 August 2017

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