IFN-β treatment requires B cells for efficacy in neuroautoimmunity. (Q35122216)

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29 February 2020

title

IFN-β treatment requires B cells for efficacy in neuroautoimmunity (English)

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1

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29 February 2020

Joel M Guthridge

7

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29 February 2020

Gabriel Pardo

8

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29 February 2020

author name string

Yang Hu

2

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29 February 2020

Gaurav Kumar

3

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29 February 2020

Spencer Szeto

4

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29 February 2020

Peter Abraham

5

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29 February 2020

Johannes Winderl

6

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29 February 2020

Jeffrey Dunn

9

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29 February 2020

Lawrence Steinman

10

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29 February 2020

Robert C Axtell

11

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29 February 2020

language of work or name

English

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publication date

2 February 2015

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29 February 2020

published in

Journal of Immunology

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volume

194

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issue

5

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29 February 2020

page(s)

2110-2116

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Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE): 52-week data (APRIL-SLE randomised trial).

29 February 2020

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A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

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Type I interferon signature is high in lupus and neuromyelitis optica but low in multiple sclerosis

28 July 2018

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Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease

28 July 2018

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Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosus

28 July 2018

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Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice

28 July 2018

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CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients

28 July 2018

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Novel human transitional B cell populations revealed by B cell depletion therapy

28 July 2018

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Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

28 July 2018

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Type I interferons protect neonates from acute inflammation through interleukin 10-producing B cells

28 July 2018

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Impact of the BAFF/BR3 axis on B cell survival, germinal center maintenance and antibody production

28 July 2018

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Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine response

28 July 2018

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G-CSF-stimulated neutrophils are a prominent source of functional BLyS

28 July 2018

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A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

28 July 2018

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Secondary B cell receptor diversification is necessary for T cell mediated neuro-inflammation during experimental autoimmune encephalomyelitis

28 July 2018

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Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions.

27 September 2018

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Role of type I interferons in the activation of autoreactive B cells

27 September 2018

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Interferon Beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers

27 September 2018

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Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity

27 September 2018

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27 September 2018

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Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

27 September 2018

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FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS

16 November 2018

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12 December 2020

Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity

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12 December 2020

Opposite effects of interferon-beta on new B and T cell release from production sites in multiple sclerosis patients

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12 December 2020

Benefits of high-dose, high-frequency interferon beta-1a in relapsing-remitting multiple sclerosis are sustained to 16 months: final comparative results of the EVIDENCE trial

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1402029

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29 February 2020

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29 February 2020

PubMed publication ID

25646307

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