The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase. (Q35131209)

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27 December 2019

title

The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase (English)

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27 December 2019

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2

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27 December 2019

5

Chaitan Khosla

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27 December 2019

author name string

Yinyan Tang

series ordinal

1

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27 December 2019

Irimpan I Mathews

series ordinal

3

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27 December 2019

David E Cane

series ordinal

4

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27 December 2019

language of work or name

English

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publication date

14 July 2006

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27 December 2019

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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27 December 2019

volume

103

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27 December 2019

issue

30

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27 December 2019

page(s)

11124-11129

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Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase

27 December 2019

cites work

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13 July 2018

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Refinement of macromolecular structures by the maximum-likelihood method

13 July 2018

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An antibiotic factory caught in action

13 July 2018

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13 July 2018

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13 July 2018

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Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase

13 July 2018

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The structure of docking domains in modular polyketide synthases

13 July 2018

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Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase

13 July 2018

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13 July 2018

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Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway

13 July 2018

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Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: a multifunctional catalytic machine

13 July 2018

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Substructure solution with SHELXD

13 July 2018

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Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

13 July 2018

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Intermodular communication in polyketide synthases: comparing the role of protein-protein interactions to those in other multidomain proteins

13 July 2018

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Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer

13 July 2018

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Substrate specificity of the loading didomain of the erythromycin polyketide synthase

13 July 2018

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The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli

13 July 2018

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The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I

13 July 2018

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Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

13 July 2018

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A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

13 July 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

13 July 2018

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Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

13 July 2018

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Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

13 July 2018

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The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

13 July 2018

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Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

13 July 2018

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The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

13 July 2018

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An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules

21 January 2018

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Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules

21 January 2018

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Intermodular communication in modular polyketide synthases: structural and mutational analysis of linker mediated protein-protein recognition

21 January 2018

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The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.

21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

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[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

21 January 2018

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Dissecting and exploiting intermodular communication in polyketide synthases

21 January 2018

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12 December 2020

Architecture of mammalian fatty acid synthase at 4.5 A resolution

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12 December 2020

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

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12 December 2020

Harnessing the biosynthetic code: combinations, permutations, and mutations

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0601924103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844787%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

0 references

1 reference

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27 December 2019

PubMed publication ID

16844787

1 reference