Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination (Q35132066)

6 August 2017

Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination (English)

1 reference

6 August 2017

1 reference

ChEBI release 2020-05-28

Eric J Huang

9

1 reference

ORCID Public Data File 2021

author name string

Stephen P J Fancy

1

1 reference

6 August 2017

Emily P Harrington

2

1 reference

6 August 2017

Tracy J Yuen

3

1 reference

6 August 2017

John C Silbereis

4

1 reference

6 August 2017

Chao Zhao

5

1 reference

6 August 2017

Sergio E Baranzini

6

1 reference

6 August 2017

Charlotte C Bruce

7

1 reference

6 August 2017

Jose J Otero

8

1 reference

6 August 2017

Roel Nusse

10

1 reference

6 August 2017

Robin J M Franklin

11

1 reference

6 August 2017

David H Rowitch

12

1 reference

6 August 2017

language of work or name

English

0 references

publication date

26 June 2011

1 reference

6 August 2017

1 reference

6 August 2017

14

1 reference

6 August 2017

8

1 reference

6 August 2017

1009-1016

1 reference

https://scigraph.springernature.com/pub.10.1038/nn.2855

6 August 2017

0 references

cites work

Retinoid X receptor gamma signaling accelerates CNS remyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Axin2 regulates chondrocyte maturation and axial skeletal development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Extensive remyelination of the CNS leads to functional recovery

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Remyelination in the CNS: from biology to therapy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Pathogenesis of cerebral white matter injury of prematurity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

NMDA receptors are expressed in oligodendrocytes and activated in ischaemia.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

LINGO-1 negatively regulates myelination by oligodendrocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Functional interaction of beta-catenin with the transcription factor LEF-1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Towards improved animal models of neonatal white matter injury associated with cerebral palsy.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Neonatal MRI to predict neurodevelopmental outcomes in preterm infants

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145042

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

27 September 2018

1 reference

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

21 January 2018

1 reference

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

21 January 2018

1 reference

Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination

21 January 2018

1 reference

Lysolecithin induces demyelination in vitro in a cerebellar slice culture system.

21 January 2018

1 reference

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21706018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wnt signaling is sufficient to perturb oligodendrocyte maturation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21706018

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NN.2855

1 reference

Dimensions Publication ID

6 August 2017

1022082261

0 references

Fatcat ID

release_dkh6uoygurd5piohakbpo7umou

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dkh6uoygurd5piohakbpo7umou

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3145042

1 reference

6 August 2017

1 reference