Deregulation of the G1/S-phase control in human testicular germ cell tumours (Q35132963)

6 August 2017

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title

Deregulation of the G1/S-phase control in human testicular germ cell tumours (English)

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6 August 2017

5

Jiri Bartek

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Jiří Lukáš

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4

object named as

Jiri Lukas

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Ewa Rajpert-De Meyts

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2

object named as

Ewa Rajpert-De Meyts

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Niels E. Skakkebæk

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3

object named as

Niels E Skakkebaek

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6 August 2017

1

Jirina Bartkova

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6 August 2017

1 January 2003

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Acta Pathologica et Microbiologica Scandinavica

6 August 2017

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6 August 2017

111

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6 August 2017

1

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6 August 2017

252-65; discussion 265-6

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Perspective: defects in cell cycle control and cancer

6 August 2017

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Mammalian G1- and S-phase checkpoints in response to DNA damage

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Genome maintenance mechanisms for preventing cancer

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The retinoblastoma protein pathway in cell cycle control and cancer

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CHK2 kinase--a busy messenger.

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The p16INK4a/CDKN2A tumor suppressor and its relatives.

21 January 2018

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Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

21 January 2018

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Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex

21 January 2018

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Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

21 January 2018

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D-type cyclins in adult human testis and testicular cancer: relation to cell type, proliferation, differentiation, and malignancy

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Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

21 January 2018

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Role of gain of 12p in germ cell tumour development

21 January 2018

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Lack of p19INK4d in human testicular germ-cell tumours contrasts with high expression during normal spermatogenesis

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The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

21 January 2018

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Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

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Atm-deficient mice: a paradigm of ataxia telangiectasia

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Genomic instability in mice lacking histone H2AX

21 January 2018

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The emerging phenotype of the testicular carcinoma in situ germ cell

21 January 2018

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Two genetic hits (more or less) to cancer

21 January 2018

1 reference

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Differential expression and regulation of the retinoblastoma family of proteins during testicular development and spermatogenesis: roles in the control of germ cell proliferation, differentiation and apoptosis

21 January 2018

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Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

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7 January 2021

Possible carcinoma-in-situ of the testis

1 reference

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7 January 2021

Correlation between retinoblastoma gene expression and differentiation in human testicular tumors

1 reference

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7 January 2021

Cell cycle regulators in testicular cancer: loss of p18INK4C marks progression from carcinoma in situ to invasive germ cell tumours

1 reference

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7 January 2021

Molecular analysis of P16(Ink4)/CDKN2 and P15(INK4B)/MTS2 genes in primary human testicular germ cell tumors

1 reference

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7 January 2021

p53 protein alterations in human testicular cancer including pre-invasive intratubular germ-cell neoplasia

1 reference

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7 January 2021

P53 tumour suppressor gene and germ cell neoplasia.

1 reference

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7 January 2021

Chk2 tumour suppressor protein in human spermatogenesis and testicular germ-cell tumours

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INK4d-deficient mice are fertile despite testicular atrophy

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7 January 2021

Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma

1 reference

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7 January 2021

The origin and biology of CIS cells: general discussion

1 reference

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7 January 2021

Pathogenesis of testicular germ cell tumours

1 reference

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A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

1 reference

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7 January 2021

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Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12760379