Switching rates of Plasmodium falciparum var genes: faster than we thought? (Q35134453)

6 August 2017

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title

Switching rates of Plasmodium falciparum var genes: faster than we thought? (English)

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6 August 2017

Plasmodium falciparum

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Michelle L Gatton

1

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author name string

Jennifer M Peters

series ordinal

2

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PubMed ID

12763425

6 August 2017

Elizabeth V Fowler

series ordinal

3

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PubMed ID

12763425

6 August 2017

Qin Cheng

series ordinal

4

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6 August 2017

1 May 2003

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6 August 2017

Trends in Parasitology

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6 August 2017

19

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6 August 2017

5

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6 August 2017

202-208

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6 August 2017

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Association of severe malaria with a specific Plasmodium falciparum genotype in French Guiana.

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The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1.

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Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children.

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Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections

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Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum

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Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes

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Rapid switching to multiple antigenic and adhesive phenotypes in malaria

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Malaria parasites undergo antigenic variation at high rates in vivo

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Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite

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Genome sequence of the human malaria parasite Plasmodium falciparum

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An update on antigenic variation in African trypanosomes

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The chromosomal organization of the Plasmodium falciparum var gene family is conserved

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Control of VSG gene expression sites

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7 January 2021

Malaria. Cooperative silencing elements in var genes.

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7 January 2021

Transcription of multiple var genes by individual, trophozoite-stage Plasmodium falciparum cells expressing a chondroitin sulphate A binding phenotype

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Expression of var genes located within polymorphic subtelomeric domains of Plasmodium falciparum chromosomes.

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High diversity and rapid changeover of expressed var genes during the acute phase of Plasmodium falciparum infections in human volunteers

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The Plasmodium falciparum var gene switching rate, switching mechanism and patterns of parasite recrudescence described by mathematical modelling.

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7 January 2021

Disruption of a novel open reading frame of Plasmodium falciparum chromosome 9 by subtelomeric and internal deletions can lead to loss or maintenance of cytoadherence

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Splenic requirement for antigenic variation and expression of the variant antigen on the erythrocyte membrane in cloned Plasmodium knowlesi malaria

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Antigenic variation of cloned Plasmodium fragile in its natural host Macaca sinica. Sequential appearance of successive variant antigenic types

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Plasmodium falciparumin the squirrel monkey (Saimiri sciureus): infection of non-splenectomised animals as a model for exploring clinical manifestations of malaria

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Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro

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A retrospective examination of sporozoite- and trophozoite-induced infections with Plasmodium falciparum: development of parasitologic and clinical immunity during primary infection

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Genetic diversity of the DBLalpha region in Plasmodium falciparum var genes among Asia-Pacific isolates

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CD4 T cell responses to a variant antigen of the malaria parasite Plasmodium falciparum, erythrocyte membrane protein-1, in individuals living in malaria-endemic areas.

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Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line

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Variant proteins on the surface of malaria-infected erythrocytes--developing vaccines.

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Plasmodium falciparum parasitaemia described by a new mathematical model.

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Identifiers

DOI

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6 August 2017

1 reference

PubMed ID

12763425