Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations (Q35134831)

6 August 2017

title

Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations (English)

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6 August 2017

1 reference

4

Burkhard Madea

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6 August 2017

5

Mark Stoneking

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6 August 2017

Mingkun Li

1

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6 August 2017

Roland Schröder

series ordinal

2

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6 August 2017

Shengyu Ni

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

9 February 2015

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

112

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6 August 2017

issue

8

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6 August 2017

page(s)

2491-2496

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Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals

6 August 2017

cites work

1 reference

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MtDNA segregation in heteroplasmic tissues is common in vivo and modulated by haplotype differences and developmental stage

13 July 2018

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Somatic mtDNA mutation spectra in the aging human putamen

13 July 2018

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Recurrent tissue-specific mtDNA mutations are common in humans

13 July 2018

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13 July 2018

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Unsolved issues related to human mitochondrial diseases

13 July 2018

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Tissue-specific mitochondrial heteroplasmy at position 16,093 within the same individual

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Hypervariable sites in the mtDNA control region are mutational hotspots

13 July 2018

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13 July 2018

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Mutations in mitochondrial DNA accumulate differentially in three different human tissues during ageing

13 July 2018

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13 July 2018

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13 July 2018

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Is selection required for the accumulation of somatic mitochondrial DNA mutations in post-mitotic cells?

27 September 2018

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Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice

27 September 2018

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Tissue-specific differences in mitochondrial activity and biogenesis

27 September 2018

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12 December 2020

Purifying selection of mtDNA and its implications for understanding evolution and mitochondrial disease

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12 December 2020

Mitochondrial DNA and disease

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12 December 2020

Varying loads of the mitochondrial DNA A3243G mutation in different tissues: implications for diagnosis

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12 December 2020

Nonrandom tissue distribution of mutant mtDNA

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12 December 2020

Detection and Quantification of the Age-Related Point Mutation A189G in the Human Mitochondrial DNA

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1419651112

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6 August 2017

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6 August 2017

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