X-ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity. (Q35135005)

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2 November 2019

title

X-ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9087491%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

main subject

X-ray crystallography

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antimalarial

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author name string

Karle JM

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9087491%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

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publication date

1 April 1997

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Antimicrobial Agents and Chemotherapy

2 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9087491%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

41

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2 November 2019

issue

4

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2 November 2019

page(s)

791-794

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Anomalous dispersion of sulfur in quinidine sulfate, (C(20)H(25)N(2)O(2))(2)SO(4).2H(2)O: Implications for structure analysis

2 November 2019

cites work

1 reference

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Electrocardiographic changes and halofantrine plasma level during acute falciparum malaria.

13 July 2018

1 reference

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Plasmodium falciparum: role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents

13 July 2018

1 reference

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Efficacy and tolerance of extended-dose halofantrine for drug-resistant falciparum malaria in Thailand

13 July 2018

1 reference

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Halofantrine versus mefloquine in treatment of multidrug-resistant falciparum malaria

13 July 2018

1 reference

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Clinical pharmacokinetics of halofantrine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=163796

Malaria: treatment efficacy of halofantrine (WR 171,669) in initial field trials in Thailand

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=163796

In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=163796

Halofantrine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic potential

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=163796

Resolution of antimalarial agents via complex formation with .alpha.-(2,4,5,7-tetranitro-9-fluorenylideneaminooxy)propionic acid

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=163796

Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=163796

Direct determination of the enantiomers of halofantrine and its pharmacologically active metabolite N-desbutylhalofantrine by high-performance liquid chromatography

27 September 2018

1 reference

12 December 2020

Structure of the antimalarial halofantrine hydrochloride

1 reference

12 December 2020

A comparison of the antimalarial activity of the cinchona alkaloids against Plasmodium falciparum in vitro

1 reference

12 December 2020

Direct determination of the enantiomers of the antimalarial drug halofantrine and its active metabolite N-desbutylhalofantrine in human plasma

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.41.4.791

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9087491%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9087491%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

9087491

1 reference