S1P is associated with protection in human and experimental cerebral malaria (Q35136728)

6 August 2017

S1P is associated with protection in human and experimental cerebral malaria (English)

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6 August 2017

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9

Kevin C Kain

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6 August 2017

8

W Conrad Liles

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6 August 2017

Constance Am Finney

1

1 reference

6 August 2017

Cheryl A Hawkes

2

1 reference

6 August 2017

Dylan C Kain

3

1 reference

6 August 2017

Aggrey Dhabangi

4

1 reference

6 August 2017

Charles Musoke

5

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6 August 2017

Christine Cserti-Gazdewich

6

1 reference

6 August 2017

Tamas Oravecz

7

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6 August 2017

language of work or name

English

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publication date

5 May 2011

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6 August 2017

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6 August 2017

17

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6 August 2017

7-8

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6 August 2017

717-725

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https://scigraph.springernature.com/pub.10.2119/molmed.2010.00214

6 August 2017

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28 July 2018

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The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.

28 July 2018

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Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules

28 July 2018

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Cellular localization of sphingosine-1-phosphate receptor 1 expression in the human central nervous system

28 July 2018

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Fingolimod is a potential novel therapy for multiple sclerosis

28 July 2018

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Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation

28 July 2018

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Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

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The murine cerebral malaria phenomenon

28 July 2018

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Homeostatic regulation of T effector to Treg ratios in an area of seasonal malaria transmission

28 July 2018

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Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children

28 July 2018

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Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

28 July 2018

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Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria

28 July 2018

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The alliance of sphingosine-1-phosphate and its receptors in immunity

28 July 2018

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Vascular endothelium as a contributor of plasma sphingosine 1-phosphate

28 July 2018

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Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1

28 July 2018

1 reference

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Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor

28 July 2018

1 reference

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Cognitive impairment after cerebral malaria in children: a prospective study

28 July 2018

1 reference

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Erythrocytes store and release sphingosine 1-phosphate in blood.

28 July 2018

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Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

28 July 2018

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A unified hypothesis for the genesis of cerebral malaria: sequestration, inflammation and hemostasis leading to microcirculatory dysfunction.

28 July 2018

1 reference

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Human cerebral malaria and the blood-brain barrier

28 July 2018

1 reference

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Sphingosine kinase: biochemical and cellular regulation and role in disease

28 July 2018

1 reference

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Astrocyte-endothelial interactions at the blood-brain barrier

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Transient T cell accumulation in lymph nodes and sustained lymphopenia in mice treated with FTY720.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

FTY720 prolongs clear corneal allograft survival with a differential effect on different lymphocyte populations

28 July 2018

1 reference

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Sphingosine 1-phosphate pathway therapeutics: a lipid ligand-receptor paradigm

28 July 2018

1 reference

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Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Sphingosine-1-phosphate: an enigmatic signalling lipid

28 July 2018

1 reference

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Innate immune response to malaria: rapid induction of IFN-gamma from human NK cells by live Plasmodium falciparum-infected erythrocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Severe falciparum malaria. World Health Organization, Communicable Diseases Cluster

28 July 2018

1 reference

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EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Role of cytokines and adhesion molecules in malaria immunopathology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

CD4+ CD25+ regulatory T cells partially mediate the beneficial effects of FTY720, a sphingosine-1-phosphate analogue, during ischaemia/reperfusion-induced acute kidney injury.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Neuropathogenesis of human and murine malaria.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Sphingosine 1-phosphate induces vascular endothelial growth factor expression in endothelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Discovery of S1P transporter may uncover the unidentified S1P-regulated signal in circulation, immunity, and bone metabolism

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

FTY720 attenuates lesional interleukin-17(+) cell accumulation in rat experimental autoimmune neuritis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Plasmodium yoelii: assessment of production and role of nitric oxide during the early stages of infection in susceptible and resistant mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Control of pathogenic CD8+ T cell migration to the brain by IFN-gamma during experimental cerebral malaria.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Prevention and cure of autoimmune diabetes in nonobese diabetic mice by continuous administration of FTY720.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Preoperative administration of FTY720 prolonged renal allograft survival

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

FTY720 inhibits tumor growth and angiogenesis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Quantitative analysis of sphingoid base-1-phosphates as bisacetylated derivatives by liquid chromatography-tandem mass spectrometry

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

FTY720 impairs necrosis development after ischemia-reperfusion injury

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

Redistribution and degeneration of retinal astrocytes in experimental murine cerebral malaria: relationship to disruption of the blood-retinal barrier.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146616

A high-performance liquid chromatographic method to measure sphingosine 1-phosphate and related compounds from sphingosine kinase assays and other biological samples

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.2119%2FMOLMED.2010.00214

Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.2119%2FMOLMED.2010.00214

10.2119/MOLMED.2010.00214

31 March 2020

Identifiers

DOI

1 reference

Dimensions Publication ID

6 August 2017

0 references

1 reference

6 August 2017

1 reference