Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants (Q35137931)

6 August 2017

Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants (English)

1 reference

6 August 2017

2

Habibul Ahsan

1 reference

6 August 2017

Brandon L Pierce

1

1 reference

PubMed ID

20813862

6 August 2017

Tyler J Vanderweele

series ordinal

3

1 reference

6 August 2017

2 September 2010

1 reference

International Journal of Epidemiology

6 August 2017

1 reference

6 August 2017

40

1 reference

6 August 2017

740-752

1 reference

6 August 2017

3

1 reference

Loci at chromosomes 13, 19 and 20 influence age at natural menopause

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association analyses identify SPOCK as a key novel gene underlying age at menarche

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Plasma lipoproteins: genetic influences and clinical implications

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

A genome-wide association study identifies three loci associated with mean platelet volume

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Variants in MTNR1B influence fasting glucose levels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Common variants at 30 loci contribute to polygenic dyslipidemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Accounting for ancestry: population substructure and genome-wide association studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

A genome-wide association study identifies protein quantitative trait loci (pQTLs)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Mendelian randomization as an instrumental variable approach to causal inference

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Estimation based on case-control designs with known prevalence probability.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genetic variation in LIN28B is associated with the timing of puberty

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association study identifies eight loci associated with blood pressure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Genome-wide association study of blood pressure and hypertension

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Instrumental variable analysis for estimation of treatment effects with dichotomous outcomes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Common variants of FUT2 are associated with plasma vitamin B12 levels

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Revealing the architecture of gene regulation: the promise of eQTL studies

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Adjusting for bias and unmeasured confounding in Mendelian randomization studies with binary responses

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

'Mendelian randomization' equals instrumental variable analysis with genetic instruments

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

C-reactive protein and its role in metabolic syndrome: mendelian randomisation study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Commentary: the concept of 'Mendelian Randomization'.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147064

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYQ151

A Survey of Weak Instruments and Weak Identification in Generalized Method of Moments

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYQ151

Causal inference with generalized structural mean models

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYQ151

Mendelian randomisation: a new spin or real progress?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20813862

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/IJE/DYQ151

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

20813862