Alterations in ornithine decarboxylase characteristics account for tolerance of Trypanosoma brucei rhodesiense to D,L-alpha-difluoromethylornithine. (Q35138030)

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English	Alterations in ornithine decarboxylase characteristics account for tolerance of Trypanosoma brucei rhodesiense to D,L-alpha-difluoromethylornithine.	scientific article

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scholarly article

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6 November 2019

Alterations in ornithine decarboxylase characteristics account for tolerance of Trypanosoma brucei rhodesiense to D,L-alpha-difluoromethylornithine (English)

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6 November 2019

Trypanosoma brucei

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Trypanosoma brucei rhodesiense infectious disease

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author name string

Iten M

1

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6 November 2019

Mett H

2

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6 November 2019

Evans A

3

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6 November 2019

Enyaru JC

4

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6 November 2019

Brun R

5

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6 November 2019

Kaminsky R

6

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6 November 2019

language of work or name

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publication date

1 September 1997

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6 November 2019

Antimicrobial Agents and Chemotherapy

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6 November 2019

41

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6 November 2019

1922-1925

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6 November 2019

9

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6 November 2019

Cloning of a trypanosomatid gene coding for an ornithine decarboxylase that is metabolically unstable even though it lacks the C-terminal degradation domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164036

13 July 2018

Innate lack of susceptibility of Ugandan Trypanosoma brucei rhodesiense to DL-alpha-difluoromethylornithine (DFMO).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164036

13 July 2018

Polyamine metabolism and function

1 reference

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13 July 2018

Epidemiological studies on the animal reservoir of gambiense sleeping sickness. Part I. Review of literature and description of the study areas

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13 July 2018

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13 July 2018

Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose.

1 reference

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13 July 2018

Cultivation in a semi-defined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164036

13 July 2018

Treatment of gambiense sleeping sickness in the Sudan with oral DFMO (DL-alpha-difluoromethylornithine), an inhibitor of ornithine decarboxylase; first field trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164036

13 July 2018

Biochemical changes associated with alpha-difluoromethylornithine uptake and resistance in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164036

13 July 2018

A Trypanosoma brucei mutant resistant to alpha-difluoromethylornithine.

1 reference

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13 July 2018

Uptake of alpha-difluoromethylornithine by Trypanosoma brucei brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164036

13 July 2018

Cloning and sequencing of the ornithine decarboxylase gene from Trypanosoma brucei. Implications for enzyme turnover and selective difluoromethylornithine inhibition.

1 reference

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13 July 2018

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

1 reference

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13 July 2018

In vitro drug sensitivity test for Trypanosoma brucei subgroup bloodstream trypomastigotes

1 reference

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13 July 2018

Treatment of arsenical refractory Rhodesian sleeping sickness in Kenya

1 reference

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13 July 2018

Trypanosoma brucei brucei: regulation of ornithine decarboxylase in procyclic forms and trypomastigotes.

1 reference

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13 July 2018

Differentiation of Trypanosoma brucei bloodstream trypomastigotes from long slender to short stumpy-like forms in axenic culture

1 reference

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13 July 2018

Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense

1 reference

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13 July 2018

Destabilization of ornithine decarboxylase by transfected antizyme gene expression in hepatoma tissue culture cells

1 reference

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13 July 2018

Resistance to DL-alpha-difluoromethylornithine by clinical isolates of Trypanosoma brucei rhodesiense. Role of S-adenosylmethionine

1 reference

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27 September 2018

In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei.

1 reference

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27 September 2018

Trypanosoma brucei brucei: expression of drug resistance in vitro.

1 reference

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27 September 2018

Eflornithine concentrations in serum and cerebrospinal fluid of 63 patients treated for Trypanosoma brucei gambiense sleeping sickness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164036

16 November 2018

Degradation of ornithine decarboxylase by the mammalian and yeast 26S proteasome complexes requires all the components of the protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9303385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine compartmentalization in various human disease states

1 reference

https://pubmed.ncbi.nlm.nih.gov/9303385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.41.9.1922

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6 November 2019

1 reference

Europe PubMed Central

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6 November 2019

1 reference

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6 November 2019

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