Stochastic receptor expression determines cell fate upon interferon treatment (Q35139921)

6 August 2017

Stochastic receptor expression determines cell fate upon interferon treatment (English)

1 reference

6 August 2017

Doron Levin

1

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6 August 2017

Daniel Harari

series ordinal

2

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6 August 2017

Gideon Schreiber

series ordinal

3

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6 August 2017

language of work or name

English

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publication date

20 June 2011

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Molecular and Cellular Biology

6 August 2017

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6 August 2017

31

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6 August 2017

16

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6 August 2017

3252-3266

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describes a project that uses

6 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3147786/fullTextXML

inferred from PubMed Central ID database lookup

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Receptor density is key to the alpha2/beta interferon differential activities.

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13 July 2018

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13 July 2018

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An interferon alpha2 mutant optimized by phage display for IFNAR1 binding confers specifically enhanced antitumor activities

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13 July 2018

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Stat-mediated signaling induced by type I and type II interferons (IFNs) is differentially controlled through lipid microdomain association and clathrin-dependent endocytosis of IFN receptors

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Identification of residues of the IFNAR1 chain of the type I human interferon receptor critical for ligand binding and biological activity

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Interferon receptor expression regulates the antiproliferative effects of interferons on cancer cells and solid tumors

13 July 2018

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Novel growth and death related interferon-stimulated genes (ISGs) in melanoma: greater potency of IFN-beta compared with IFN-alpha2.

13 July 2018

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Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry

13 July 2018

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Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking

13 July 2018

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Preferential induction of apoptosis by interferon (IFN)-beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines.

13 July 2018

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New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface

13 July 2018

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13 July 2018

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Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity

13 July 2018

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How cells respond to interferons

13 July 2018

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Biologic activities of natural and synthetic type I interferons.

13 July 2018

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Elucidation of the basic three-dimensional structure of type I interferons and its functional and evolutionary implications.

13 July 2018

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Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha

13 July 2018

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13 July 2018

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Ligand-induced association of the type I interferon receptor components

13 July 2018

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Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster

13 July 2018

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Growth inhibitory effects of interferon-beta but not interferon-alpha on human glioma cells: correlation of receptor binding, 2',5'-oligoadenylate synthetase and protein kinase activity

13 July 2018

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A protein tyrosine kinase in the interferon alpha/beta signaling pathway

13 July 2018

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Interactions between double-stranded RNA regulators and the protein kinase DAI

13 July 2018

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Insulin receptor: covalent labeling and identification of subunits

13 July 2018

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The stability of the ternary interferon-receptor complex rather than the affinity to the individual subunits dictates differential biological activities.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147786

Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147786

Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147786

Ligand-induced assembling of the type I interferon receptor on supported lipid bilayers.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147786

Stochastic protein expression in individual cells at the single molecule level

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147786

Interferon-induced cell cycle changes in human hematopoietic cell lines and fresh leukemic cells

8 December 2018

1 reference

12 December 2020

Variations in the unstructured C-terminal tail of interferons contribute to differential receptor binding and biological activity

1 reference

12 December 2020

Comparison of gene expression patterns induced by treatment of human umbilical vein endothelial cells with IFN-alpha 2b vs. IFN-beta 1a: understanding the functional relationship between distinct type I interferons that act through a common receptor

1 reference

12 December 2020

Interferon alpha receptors are important for antiproliferative effect of interferon-alpha against human hepatocellular carcinoma cells

1 reference

12 December 2020

67 Purification and characterization of human leukocyte interferons by high-performance liquid chromatography

1 reference

12 December 2020

Activation of the Jak-Stat Pathway in Cells That Exhibit Selective Sensitivity to the Antiviral Effects of IFN-beta Compared with IFN-alpha

1 reference

12 December 2020

Differential responses to IFN-alpha subtypes in human T cells and dendritic cells

1 reference

12 December 2020

Initial expression of interferon alpha receptor 2 (IFNAR2) on CD34-positive cells and its down-regulation correlate with clinical response to interferon therapy in chronic myelogenous leukemia

1 reference

12 December 2020

Cytocidal Effect of Interferons on Porcine Renal Cells

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.05251-11

1 reference

6 August 2017

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6 August 2017

1 reference