Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants. (Q35140450)

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English	Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants.	scientific article

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2 February 2020

Detection of minority resistance during early HIV-1 infection: natural variation and spurious detection rather than transmission and evolution of multiple viral variants (English)

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2 February 2020

HIV transmission

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2 February 2020

Sergei L. Kosakovsky Pond

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Sergei L Kosakovsky Pond

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Sara Gianella

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Susan J Little

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2 February 2020

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Wayne Delport

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2 February 2020

Mary E Pacold

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2 February 2020

Jason A Young

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Douglas D Richman

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1 June 2011

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2 February 2020

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9

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Journal of Virology

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85

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2 February 2020

8359-8367

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2 February 2020

Low-frequency HIV-1 drug resistance mutations and risk of NNRTI-based antiretroviral treatment failure: a systematic review and pooled analysis

1 reference

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13 July 2018

Comparison of methods to detect HIV dual infection

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13 July 2018

Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

1 reference

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Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

1 reference

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Minority variants of drug-resistant HIV.

1 reference

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13 July 2018

Nucleic acid template and the risk of a PCR-Induced HIV-1 drug resistance mutation

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13 July 2018

Prevalence and clinical significance of HIV drug resistance mutations by ultra-deep sequencing in antiretroviral-naïve subjects in the CASTLE study

1 reference

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High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men.

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Wide variation in the multiplicity of HIV-1 infection among injection drug users

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13 July 2018

The prevalence of transmitted antiretroviral drug resistance in treatment-naive HIV-infected individuals in China

1 reference

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13 July 2018

Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure

1 reference

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13 July 2018

An evolutionary model-based algorithm for accurate phylogenetic breakpoint mapping and subtype prediction in HIV-1

1 reference

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Phylogenetic analysis of population-based and deep sequencing data to identify coevolving sites in the nef gene of HIV-1.

1 reference

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13 July 2018

Transmission of drug-resistant HIV-1 is stabilizing in Europe

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13 July 2018

Minority variants associated with transmitted and acquired HIV-1 nonnucleoside reverse transcriptase inhibitor resistance: implications for the use of second-generation nonnucleoside reverse transcriptase inhibitors

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13 July 2018

The efficiency of single genome amplification and sequencing is improved by quantitation and use of a bioinformatics tool

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13 July 2018

Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants

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Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1

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13 July 2018

Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3147985

13 July 2018

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

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N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance

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Systematic evaluation of allele-specific real-time PCR for the detection of minor HIV-1 variants with pol and env resistance mutations

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13 July 2018

Simple PCR assays improve the sensitivity of HIV-1 subtype B drug resistance testing and allow linking of resistance mutations

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Characterization of mutation spectra with ultra-deep pyrosequencing: application to HIV-1 drug resistance

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Genotypic predictors of human immunodeficiency virus type 1 drug resistance

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13 July 2018

The K101P and K103R/V179D mutations in human immunodeficiency virus type 1 reverse transcriptase confer resistance to nonnucleoside reverse transcriptase inhibitors

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13 July 2018

The impact of transmitted drug resistance on the natural history of HIV infection and response to first-line therapy

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13 July 2018

TMC125 displays a high genetic barrier to the development of resistance: evidence from in vitro selection experiments

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Genome sequencing in microfabricated high-density picolitre reactors

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Datamonkey: rapid detection of selective pressure on individual sites of codon alignments

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13 July 2018

Not so different after all: a comparison of methods for detecting amino acid sites under selection

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Bayes empirical bayes inference of amino acid sites under positive selection

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Risk of failure in patients with 215 HIV-1 revertants starting their first thymidine analog-containing highly active antiretroviral therapy

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Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection

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13 July 2018

Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors

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13 July 2018

Implications of antiretroviral resistance on viral fitness

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Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy

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13 July 2018

Prevalence and conditions of selection of E44D/A and V118I human immunodeficiency virus type 1 reverse transcriptase mutations in clinical practice

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13 July 2018

A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V

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Base-calling of automated sequencer traces using phred. II. Error probabilities

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Base-calling of automated sequencer traces using phred. I. Accuracy assessment

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A novel mutation (F227L) arises in the reverse transcriptase of human immunodeficiency virus type 1 on dose-escalating treatment of HIV type 1-infected cell cultures with the nonnucleoside reverse transcriptase inhibitor thiocarboxanilide UC-781.

1 reference

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1 reference

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13 July 2018

Low level of the K103N HIV-1 above a threshold is associated with virological failure in treatment-naive individuals undergoing efavirenz-containing therapy.

1 reference

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1 reference

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27 September 2018

Low-frequency K103N strengthens the impact of transmitted drug resistance on virologic responses to first-line efavirenz or nevirapine-based highly active antiretroviral therapy

1 reference

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27 September 2018

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1 reference

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27 September 2018

Detection of human immunodeficiency virus (HIV) type 1 M184V and K103N minority variants in patients with primary HIV infection.

1 reference

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27 September 2018

Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients

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27 September 2018

Transmission of HIV-1 minority-resistant variants and response to first-line antiretroviral therapy.

1 reference

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27 September 2018

Preexisting resistance to nonnucleoside reverse-transcriptase inhibitors predicts virologic failure of an efavirenz-based regimen in treatment-naive HIV-1-infected subjects

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27 September 2018

Transmission of HIV-1 drug resistance in Switzerland: a 10-year molecular epidemiology survey.

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27 September 2018

A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection

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27 September 2018

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1 reference

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27 September 2018

Detection of minor populations of drug-resistant HIV-1 in acute seroconverters.

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27 September 2018

Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions

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27 September 2018

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27 September 2018

Evolving patterns of HIV-1 resistance to antiretroviral agents in newly infected individuals

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27 September 2018

Prevalence of the mutational pattern E44D/A and/or V118I in the reverse transcriptase (RT) gene of HIV-1 in relation to treatment with nucleoside analogue RT inhibitors

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27 September 2018

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25 October 2018

Increased detection of HIV-1 drug resistance at time of diagnosis by testing viral DNA with a sensitive assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmission of HIV‐1 Drug‐Resistant Variants: Prevalence and Effect on Treatment Outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deep sequencing of a genetically heterogeneous sample: local haplotype reconstruction and read error correction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632754

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.02582-10

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Europe PubMed Central

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2 February 2020

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Europe PubMed Central

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2 February 2020

1 reference

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2 February 2020

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