Microglial functions and proteases (Q35141400)

6 August 2017

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title

Microglial functions and proteases (English)

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6 August 2017

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Hiroshi Nakanishi

1

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6 August 2017

1 April 2003

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6 August 2017

Molecular Neurobiology

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6 August 2017

27

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6 August 2017

2

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6 August 2017

163-176

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https://scigraph.springernature.com/pub.10.1385/mn:27:2:163

6 August 2017

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cites work

Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia

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12 December 2020

Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation

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12 December 2020

Tissue plasminogen activator is required for striatal post-ischemic synaptic potentiation

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12 December 2020

Microglial secreted cathepsin B induces neuronal apoptosis.

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12 December 2020

Different roles for thiol and aspartyl proteases in antigen presentation of ovalbumin

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12 December 2020

Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons

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12 December 2020

Tissue plasminogen activator protects hippocampal neurons from oxygen-glucose deprivation injury

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12 December 2020

Regulation of cathepsin E expression during human B cell differentiation in vitro

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12 December 2020

Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II.

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12 December 2020

Brain glia release factors with opposing actions upon neuronal survival.

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12 December 2020

Cathepsin D is involved in the clearance of Alzheimer's beta-amyloid protein.

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12 December 2020

Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation

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12 December 2020

Cathepsin D, but not cathepsin B, releases T cell stimulatory fragments from lysozyme that are functional in the context of multiple murine class II MHC molecules

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12 December 2020

Endosomal aspartic proteinases are required for invariant-chain processing

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12 December 2020

The effects of human immunodeficiency virus in the central nervous system

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12 December 2020

Developmental plasticity of CNS microglia

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12 December 2020

Scavenger receptor class B type I (SR-BI) mediates adhesion of neonatal murine microglia to fibrillar beta-amyloid

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12 December 2020

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation

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12 December 2020

Role of cathepsin D in antigen presentation of ovalbumin

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12 December 2020

Laminin degradation by plasmin regulates long-term potentiation

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12 December 2020

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons

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12 December 2020

Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells.

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12 December 2020

Involvement of caspase 3-like protease in methylmercury-induced apoptosis of primary cultured rat cerebral microglia.

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12 December 2020

Modulatory effect of plasminogen on NMDA-induced increase in intracellular free calcium concentration in rat cultured hippocampal neurons.

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12 December 2020

Potentiation of NMDA receptor function by the serine protease thrombin

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12 December 2020

Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system

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12 December 2020

Increased calpain expression in activated glial and inflammatory cells in experimental allergic encephalomyelitis

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12 December 2020

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

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12 December 2020

Microglia isolated from rat brain secrete a urokinase-type plasminogen activator

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12 December 2020

Microglial cathepsin B: an immunological examination of cellular and secreted species.

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12 December 2020

Cathepsin B-mediated activation of the proinflammatory caspase-11.

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12 December 2020

Lesion-induced transient suppression of inhibitory function in rat neocortex in vitro.

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12 December 2020

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

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12 December 2020

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

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12 December 2020

Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E

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12 December 2020

Molecular consequences of activated microglia in the brain: overactivation induces apoptosis.

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12 December 2020

Involvement of caspase-like proteinases in apoptosis of neuronal PC12 cells and primary cultured microglia induced by 6-hydroxydopamine

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12 December 2020

Participation of protease-activated receptor-1 in thrombin-induced microglial activation

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12 December 2020

Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism

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12 December 2020

Immunocompetent astrocytes and microglia display major differences in the processing of the invariant chain and in the expression of active cathepsin L and cathepsin S.

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12 December 2020

Dual role of inflammatory stimuli in activation-induced cell death of mouse microglial cells. Initiation of two separate apoptotic pathways via induction of interferon regulatory factor-1 and caspase-11.

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12 December 2020

The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

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12 December 2020

Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice.

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12 December 2020

Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways

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12 December 2020

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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12 December 2020

Rat microglial cells secrete predominantly the precursor of interleukin-1beta in response to lipopolysaccharide.

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12 December 2020

Pepstatin A-sensitive aspartic proteases in lysosome are involved in degradation of the invariant chain and antigen-processing in antigen presenting cells of mice infected with Leishmania major.

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12 December 2020

Proteases involved in MHC class II antigen presentation

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12 December 2020

Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity

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12 December 2020

Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B

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12 December 2020

Microglial apoptosis induced by chromogranin A is mediated by mitochondrial depolarisation and the permeability transition but not by cytochrome c release

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12 December 2020

Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice

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12 December 2020

Degradation of Alzheimer's beta-amyloid protein by human cathepsin D.

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12 December 2020

Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia

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12 December 2020

Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway.

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12 December 2020

Cathepsins and compartmentalization in antigen presentation

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12 December 2020

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

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12 December 2020

Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro

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12 December 2020

Biochemical analysis of proteasomes from mouse microglia: induction of immunoproteasomes by interferon-gamma and lipopolysaccharide

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12 December 2020

Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.

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12 December 2020

N-methyl-D-aspartate receptor-mediated, prolonged afterdischarges of CA1 pyramidal cells following transient cerebral ischemia in the rat hippocampus in vivo

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12 December 2020

Expression of rat cathepsin S in phagocytic cells

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12 December 2020

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

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12 December 2020

Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells

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12 December 2020

Identifiers

DOI

10.1385/MN:27:2:163

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PubMed ID

12777686

Dimensions Publication ID

6 August 2017

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1 reference

PubMed ID

12777686