Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity (Q35141643)

6 August 2017

title

Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity (English)

1 reference

6 August 2017

0 references

10

Jacques Pouyssegur

1 reference

6 August 2017

Paul Moynagh

9

1 reference

ORCID Public Data File 2021

Catherine Godson

object named as

Catherine Godson

7

1 reference

ORCID Public Data File 2021

author name string

Eoin P Cummins

1

1 reference

6 August 2017

Edurne Berra

2

1 reference

6 August 2017

Katrina M Comerford

3

1 reference

6 August 2017

Amandine Ginouves

4

1 reference

6 August 2017

Kathleen T Fitzgerald

5

1 reference

6 August 2017

Fergal Seeballuck

6

1 reference

6 August 2017

Jens E Nielsen

8

1 reference

6 August 2017

Cormac T Taylor

11

1 reference

6 August 2017

language of work or name

English

0 references

publication date

17 November 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

103

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6 August 2017

issue

48

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6 August 2017

page(s)

18154-18159

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The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling

6 August 2017

cites work

1 reference

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28 July 2018

The NF-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

NF-kappaB: linking inflammation and immunity to cancer development and progression

28 July 2018

1 reference

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Signalling hypoxia by HIF hydroxylases

28 July 2018

1 reference

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Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

28 July 2018

1 reference

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Mechanism of von Hippel-Lindau protein-mediated suppression of nuclear factor kappa B activity

28 July 2018

1 reference

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Hypoxia-responsive transcription factors.

28 July 2018

1 reference

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Proline hydroxylation and gene expression

28 July 2018

1 reference

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VHL expression in renal cell carcinoma sensitizes to bortezomib (PS-341) through an NF-kappaB-dependent mechanism.

28 July 2018

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Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling.

28 July 2018

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

28 July 2018

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Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways

28 July 2018

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Oxygen sensing by HIF hydroxylases

28 July 2018

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IkappaB kinases: key regulators of the NF-kappaB pathway

28 July 2018

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Leu-574 of human HIF-1alpha is a molecular determinant of prolyl hydroxylation

28 July 2018

1 reference

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

28 July 2018

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Targeting HIF-1 for cancer therapy

28 July 2018

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Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia

28 July 2018

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

28 July 2018

1 reference

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Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

28 July 2018

1 reference

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Hypoxia--a key regulatory factor in tumour growth

28 July 2018

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

28 July 2018

1 reference

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Inflammation and cancer: back to Virchow?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha.

28 July 2018

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Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1643842

The von Hippel-Lindau tumor suppressor protein sensitizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factor-kappaB-dependent antiapoptotic pathway

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17114296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Critical role of cAMP response element binding protein expression in hypoxia-elicited induction of epithelial tumor necrosis factor-alpha.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17114296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17114296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0602235103

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference