Ubiquitin ligase gp78 targets unglycosylated prion protein PrP for ubiquitylation and degradation. (Q35143098)

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13 March 2020

title

Ubiquitin ligase gp78 targets unglycosylated prion protein PrP for ubiquitylation and degradation (English)

1 reference

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13 March 2020

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3

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13 March 2020

Yien Che Tsai

4

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13 March 2020

author name string

Jia Shao

1

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13 March 2020

Vitnary Choe

2

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13 March 2020

Allan M Weissman

5

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13 March 2020

Shiwen Luo

6

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13 March 2020

Hai Rao

7

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13 March 2020

language of work or name

English

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publication date

8 April 2014

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13 March 2020

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13 March 2020

volume

9

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13 March 2020

issue

4

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13 March 2020

page(s)

e92290

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Creative Commons CC0 License

13 March 2020

copyright license

start time

8 April 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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11 June 2022

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: the early history of ERAD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Intracellular protein degradation: from a vague idea through the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

The ubiquitin-proteasome system of Saccharomyces cerevisiae

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Prion propagation, toxicity and degradation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

The role of cofactors in prion propagation and infectivity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Misfolded PrP and a novel mechanism of proteasome inhibition

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

HECT and RING finger families of E3 ubiquitin ligases at a glance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

The ubiquitin proteasome system in neurodegenerative diseases: culprit, accomplice or victim?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Genetics of prion disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Stressing the ubiquitin-proteasome system

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Retrotranslocation of prion proteins from the endoplasmic reticulum by preventing GPI signal transamidation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Pathogenesis of prion diseases: current status and future outlook

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Evolving views in prion glycosylation: functional and pathological implications

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Proteasome inhibitors promote the sequestration of PrPSc into aggresomes within the cytosol of prion-infected CAD neuronal cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3979651

Cellular tolerance of prion protein PrP in yeast involves proteolysis and the unfolded protein response

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24714645

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12 December 2020

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Identifiers

DOI

10.1371/JOURNAL.PONE.0092290

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13 March 2020

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13 March 2020

PubMed publication ID

24714645

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24714645%20AND%20SRC:MED&resulttype=core&format=json