Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I). (Q35144837)

6 August 2017

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I). (English)

1 reference

6 August 2017

Narsis Kiani

6

0 references

Lars Kaderali

Lars Kaderali

7

0 references

Marco Binder

Marco Binder

1

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Volker Lohmann

Volker Lohmann

8

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Ralf Bartenschlager

Ralf Bartenschlager

10

0 references

Alexander Dalpke

9

Alexander Dalpke

1 reference

6 August 2017

Florian Eberle

2

1 reference

6 August 2017

Stefan Seitz

3

1 reference

6 August 2017

Norbert Mücke

4

1 reference

6 August 2017

Christian M Hüber

5

1 reference

6 August 2017

language of work or name

English

0 references

publication date

9 June 2011

1 reference

Journal of Biological Chemistry

6 August 2017

1 reference

6 August 2017

286

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6 August 2017

31

1 reference

6 August 2017

27278-27287

1 reference

describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3149321/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate

1 reference

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Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

13 July 2018

1 reference

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The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

13 July 2018

1 reference

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Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

13 July 2018

1 reference

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The chase for the RIG-I ligand--recent advances

13 July 2018

1 reference

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RIG-I detects viral genomic RNA during negative-strand RNA virus infection

13 July 2018

1 reference

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Activation of MDA5 requires higher-order RNA structures generated during virus infection

13 July 2018

1 reference

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Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

13 July 2018

1 reference

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5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

13 July 2018

1 reference

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Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

13 July 2018

1 reference

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Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA.

13 July 2018

1 reference

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RIG-I and dsRNA-induced IFNbeta activation

13 July 2018

1 reference

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Accessing the therapeutic potential of immunostimulatory nucleic acids

13 July 2018

1 reference

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Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

13 July 2018

1 reference

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Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

13 July 2018

1 reference

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Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

13 July 2018

1 reference

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Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity

13 July 2018

1 reference

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The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

13 July 2018

1 reference

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Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

13 July 2018

1 reference

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Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

13 July 2018

1 reference

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Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy

13 July 2018

1 reference

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Function of RIG-I-like receptors in antiviral innate immunity

13 July 2018

1 reference

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5'-Triphosphate RNA is the ligand for RIG-I

13 July 2018

1 reference

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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

13 July 2018

1 reference

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

13 July 2018

1 reference

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Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection

13 July 2018

1 reference

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149321

VISA is an adapter protein required for virus-triggered IFN-beta signaling

13 July 2018

1 reference

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149321

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149321

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149321

Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149321

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149321

Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3149321

Scanning force microscopy of DNA deposited onto mica: equilibration versus kinetic trapping studied by statistical polymer chain analysis.

13 July 2018

1 reference

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RIGorous detection: exposing virus through RNA sensing.

13 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.256974

21 January 2018

Identifiers

DOI

10.1074/JBC.M111.256974

1 reference

6 August 2017

1 reference

6 August 2017

1 reference