Finding genes underlying risk of complex disease by linkage disequilibrium mapping (Q35145885)

6 August 2017

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title

Finding genes underlying risk of complex disease by linkage disequilibrium mapping (English)

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6 August 2017

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linkage disequilibrium

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Andrew G Clark

1

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ORCID Public Data File 2021

publication date

1 June 2003

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Current Opinion in Genetics & Development

6 August 2017

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6 August 2017

13

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6 August 2017

3

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6 August 2017

296-302

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The future of genetic studies of complex human diseases

6 August 2017

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Linkage disequilibrium mapping in isolated founder populations: diastrophic dysplasia in Finland

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Patterns of linkage disequilibrium in the human genome

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

A comparison of linkage disequilibrium measures for fine-scale mapping

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Linkage disequilibrium in the human genome

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

The structure of haplotype blocks in the human genome

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

A first-generation linkage disequilibrium map of human chromosome 22

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

An apportionment of human DNA diversity

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Patterns of human diversity, within and among continents, inferred from biallelic DNA polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Linkage disequilibrium and the search for complex disease genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Case-control studies of association in structured or admixed populations.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Sequence variations in the public human genome data reflect a bottlenecked population history

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Linkage disequilibrium in humans: models and data

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

MULTIFACTORIAL GENETICSUNDERSTANDING QUANTITATIVE GENETIC VARIATION

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Searching for genetic determinants in the new millennium

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Maneuvering in the complex path from genotype to phenotype

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

How many diseases does it take to map a gene with SNPs?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Linkage disequilibrium and the mapping of complex human traits

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Linkage disequilibrium: what history has to tell us.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

The sampling theory of selectively neutral alleles

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

On the allelic spectrum of human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Are rare variants responsible for susceptibility to complex diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

The allelic architecture of human disease genes: common disease-common variant... or not?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Optimality, mutation and the evolution of ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

A polygenic basis for late-onset disease

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Complex signatures of natural selection at the Duffy blood group locus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Adaptive protein evolution at the Adh locus in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Interrogating a high-density SNP map for signatures of natural selection

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

High-resolution haplotype structure in the human genome

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21.

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Using haplotype blocks to map human complex trait loci

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Why is there so little intragenic linkage disequilibrium in humans?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Haplotype tagging for the identification of common disease genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

A New Statistical Method for Haplotype Reconstruction from Population Data

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Inference of haplotypes from samples of diploid populations: complexity and algorithms

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

High-throughput screening for evidence of association by using mass spectrometry genotyping on DNA pools

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

A comprehensive review of genetic association studies

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

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https://api.crossref.org/works/10.1016%2FS0959-437X%2803%2900056-X

7 January 2021

10.1016/S0959-437X(03)00056-X

Identifiers

DOI

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6 August 2017

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PubMed ID

12787793