Protein targeting and degradation are coupled for elimination of mislocalized proteins (Q35147351)

6 August 2017

title

Protein targeting and degradation are coupled for elimination of mislocalized proteins (English)

1 reference

6 August 2017

author

Ramanujan Shankar Hegde

6

1 reference

6 August 2017

Tara Hessa

1

1 reference

6 August 2017

Ajay Sharma

2

1 reference

6 August 2017

Malaiyalam Mariappan

3

1 reference

6 August 2017

Heather D Eshleman

4

1 reference

6 August 2017

Erik Gutierrez

5

1 reference

6 August 2017

language of work or name

English

0 references

publication date

10 July 2011

1 reference

6 August 2017

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6 August 2017

volume

475

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6 August 2017

issue

7356

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6 August 2017

page(s)

394-397

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A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation

6 August 2017

cites work

1 reference

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13 July 2018

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Compartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo

13 July 2018

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13 July 2018

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13 July 2018

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A ribosome-associating factor chaperones tail-anchored membrane proteins

13 July 2018

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13 July 2018

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Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins

13 July 2018

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13 July 2018

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13 July 2018

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Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein

13 July 2018

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Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

13 July 2018

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Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration

13 July 2018

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Delivering proteins for export from the cytosol

13 July 2018

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A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnel

13 July 2018

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Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.

13 July 2018

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Reduced translocation of nascent prion protein during ER stress contributes to neurodegeneration

13 July 2018

1 reference

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Retrotranslocation of prion proteins from the endoplasmic reticulum by preventing GPI signal transamidation

13 July 2018

1 reference

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Identification of a targeting factor for posttranslational membrane protein insertion into the ER

13 July 2018

1 reference

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Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

13 July 2018

1 reference

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The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system

13 July 2018

1 reference

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Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein

13 July 2018

1 reference

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Protection from cytosolic prion protein toxicity by modulation of protein translocation

13 July 2018

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The efficiency of protein compartmentalization into the secretory pathway

13 July 2018

1 reference

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CHIP: a link between the chaperone and proteasome systems

13 July 2018

1 reference

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Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region

13 July 2018

1 reference

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Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane

13 July 2018

1 reference

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Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel

13 July 2018

1 reference

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The signal recognition particle

13 July 2018

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Organelle pH studies using targeted avidin and fluorescein-biotin

13 July 2018

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Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle

13 July 2018

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Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle

13 July 2018

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A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum

13 July 2018

1 reference

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Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

27 September 2018

1 reference

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Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

27 September 2018

1 reference

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Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

27 September 2018

1 reference

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Signal sequences control gating of the protein translocation channel in a substrate-specific manner

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150218

Diffusional mobility of Golgi proteins in membranes of living cells

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21743475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10181

1 reference

Dimensions Publication ID

6 August 2017

0 references

1 reference

6 August 2017

1 reference