Cartilage oligomeric matrix protein promotes cell attachment via two independent mechanisms involving CD47 and alphaVbeta3 integrin (Q35149818)

6 August 2017

Cartilage oligomeric matrix protein promotes cell attachment via two independent mechanisms involving CD47 and alphaVbeta3 integrin (English)

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6 August 2017

Matthew J Rock

1

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6 August 2017

Paul Holden

series ordinal

2

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6 August 2017

William A Horton

series ordinal

3

1 reference

6 August 2017

Daniel H Cohn

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4

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6 August 2017

24 December 2009

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Molecular and Cellular Biochemistry

6 August 2017

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6 August 2017

338

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6 August 2017

1-2

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6 August 2017

215-224

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https://scigraph.springernature.com/pub.10.1007/s11010-009-0355-3

6 August 2017

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The effect of the single substitution of arginine within the RGD tripeptide motif of a modified neurotoxin dendroaspin on its activity of platelet aggregation and cell adhesion

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Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins

13 July 2018

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Secretion of cartilage oligomeric matrix protein is affected by the signal peptide.

13 July 2018

1 reference

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COMP mutations, chondrocyte function and cartilage matrix

13 July 2018

1 reference

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Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein.

13 July 2018

1 reference

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Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias

13 July 2018

1 reference

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Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats

13 July 2018

1 reference

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Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins

13 July 2018

1 reference

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Novel types of COMP mutations and genotype-phenotype association in pseudoachondroplasia and multiple epiphyseal dysplasia.

13 July 2018

1 reference

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Pseudoachondroplasia is caused through both intra- and extracellular pathogenic pathways

13 July 2018

1 reference

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Pseudoachondroplasia and multiple epiphyseal dysplasia: mutation review, molecular interactions, and genotype to phenotype correlations

13 July 2018

1 reference

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Thrombospondins: multifunctional regulators of cell interactions

13 July 2018

1 reference

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Thrombospondins as matricellular modulators of cell function

13 July 2018

1 reference

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Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX

13 July 2018

1 reference

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Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42

13 July 2018

1 reference

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Cartilage oligomeric matrix protein is a calcium-binding protein, and a mutation in its type 3 repeats causes conformational changes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Cell-matrix adhesions differentially regulate fascin phosphorylation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Diverse mutations in the gene for cartilage oligomeric matrix protein in the pseudoachondroplasia-multiple epiphyseal dysplasia disease spectrum

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Thrombospondin modulates alpha v beta 3 function through integrin-associated protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Mutations in the cartilage oligomeric matrix protein (COMP) gene in pseudoachondroplasia and multiple epiphyseal dysplasia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Characterization of human and mouse cartilage oligomeric matrix protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Cell-type specific adhesive interactions of skeletal myoblasts with thrombospondin-1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Expression of PSACH-associated mutant COMP in tendon fibroblasts leads to increased apoptotic cell death irrespective of the secretory characteristics of mutant COMP.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Disruption of extracellular matrix structure may cause pseudoachondroplasia phenotypes in the absence of impaired cartilage oligomeric matrix protein secretion.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Chondrocyte cell death and intracellular distribution of COMP and type IX collagen in the pseudoachondroplasia growth plate

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

An amyloid-like C-terminal domain of thrombospondin-1 displays CD47 agonist activity requiring both VVM motifs

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Regulation of integrin function by CD47 ligands. Differential effects on alpha vbeta 3 and alpha 4beta1 integrin-mediated adhesion

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Selective intracellular retention of extracellular matrix proteins and chaperones associated with pseudoachondroplasia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Cartilage oligomeric matrix protein interacts with type IX collagen, and disruptions to these interactions identify a pathogenetic mechanism in a bone dysplasia family.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150962

Physiological and pathological secretion of cartilage oligomeric matrix protein by cells in culture

27 September 2018

1 reference

12 December 2020

Novel and recurrent mutations in the C-terminal domain of COMP cluster in two distinct regions and result in a spectrum of phenotypes within the pseudoachondroplasia -- multiple epiphyseal dysplasia disease group

1 reference

12 December 2020

A cartilage oligomeric matrix protein mutation associated with pseudoachondroplasia changes the structural and functional properties of the type 3 domain

1 reference

12 December 2020

Delta 469 mutation in the type 3 repeat calcium binding domain of cartilage oligomeric matrix protein (COMP) disrupts calcium binding

1 reference

12 December 2020

Disease-causing mutations in cartilage oligomeric matrix protein cause an unstructured Ca2+ binding domain

1 reference

12 December 2020

Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage

1 reference

12 December 2020

Cartilage oligomeric matrix protein and thrombospondin 1. Purification from articular cartilage, electron microscopic structure, and chondrocyte binding

1 reference

12 December 2020

Identification of a receptor candidate for the carboxyl-terminal cell binding domain of thrombospondins

1 reference

12 December 2020

Cartilage oligomeric matrix protein: isolation and characterization from human articular cartilage

1 reference

12 December 2020

The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi

1 reference

12 December 2020

10.1007/S11010-009-0355-3

Identifiers

DOI

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6 August 2017

1 reference

6 August 2017

1 reference