Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial (Q35150645)

6 August 2017

Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial (English)

1 reference

6 August 2017

0 references

3

Sophie Namasopo

1 reference

6 August 2017

10

Kevin C Kain

1 reference

6 August 2017

9

Chandy C John

1 reference

6 August 2017

2

Robert O Opoka

1 reference

6 August 2017

Michael Hawkes

1

0 references

James V Lavery

series ordinal

6

object named as

James V Lavery

1 reference

6 August 2017

5

Kevin E Thorpe

1 reference

ORCID Public Data File 2021

6 August 2017

1 reference

W Conrad Liles

series ordinal

8

object named as

W Conrad Liles

1 reference

6 August 2017

Christopher Miller

4

1 reference

PubMed ID

21752262

6 August 2017

Andrea L Conroy

series ordinal

7

1 reference

6 August 2017

13 July 2011

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6 August 2017

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6 August 2017

12

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6 August 2017

176

1 reference

https://scigraph.springernature.com/pub.10.1186/1745-6215-12-176

6 August 2017

0 references

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13 July 2018

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Adjunctive therapy for cerebral malaria and other severe forms of Plasmodium falciparum malaria

13 July 2018

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13 July 2018

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Artemisinin derivatives versus quinine for cerebral malaria in African children: a systematic review

13 July 2018

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Increased asymmetric dimethylarginine in severe falciparum malaria: association with impaired nitric oxide bioavailability and fatal outcome

13 July 2018

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13 July 2018

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Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria

13 July 2018

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Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings

13 July 2018

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Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children

13 July 2018

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Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria

13 July 2018

1 reference

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Cerebral malaria in children is associated with long-term cognitive impairment

13 July 2018

1 reference

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Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1

13 July 2018

1 reference

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Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

13 July 2018

1 reference

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Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria

13 July 2018

1 reference

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Grand challenges in global health: community engagement in research in developing countries

13 July 2018

1 reference

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Thrombocytopenia and release of activated von Willebrand Factor during early Plasmodium falciparum malaria

13 July 2018

1 reference

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Advances in malaria diagnosis

13 July 2018

1 reference

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Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis.

13 July 2018

1 reference

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Cognitive impairment after cerebral malaria in children: a prospective study

13 July 2018

1 reference

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Nitric oxide for respiratory failure in infants born at or near term

13 July 2018

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Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial.

13 July 2018

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Assent in paediatric research: theoretical and practical considerations

13 July 2018

1 reference

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Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

13 July 2018

1 reference

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Severe malaria in children in areas with low, moderate and high transmission intensity in Uganda.

13 July 2018

1 reference

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Inhaled nitric oxide therapy in adults

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

A review of the quality of randomized clinical trials of adjunctive therapy for the treatment of cerebral malaria

13 July 2018

1 reference

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Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Nitric oxide production and signaling in inflammation.

13 July 2018

1 reference

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Management of severe malaria in children: proposed guidelines for the United Kingdom

13 July 2018

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Nitric oxide bioavailability in malaria

13 July 2018

1 reference

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Inhaled nitric oxide treatment of patients with pulmonary tuberculosis evidenced by positive sputum smears

13 July 2018

1 reference

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Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.

13 July 2018

1 reference

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Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease

13 July 2018

1 reference

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Cost of nitric oxide is exorbitant

13 July 2018

1 reference

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Nitric oxide and the immune response

13 July 2018

1 reference

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Nitric oxide synthase 2(Lambaréné) (G-954C), increased nitric oxide production, and protection against malaria

13 July 2018

1 reference

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Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

13 July 2018

1 reference

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Statistical quality control in clinical trials

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

A controlled trial of artemether or quinine in Vietnamese adults with severe falciparum malaria

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Toxicity of nitrogen dioxide: an introduction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

An immunohistochemical study of the pathology of fatal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Random-effects models for longitudinal data

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment

13 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Low plasma arginine concentrations in children with cerebral malaria and decreased nitric oxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

The CCTTT pentanucleotide microsatellite in iNOS promoter influences the clinical outcome in P. falciparum infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Significant association of longer forms of CCTTT Microsatellite repeat in the inducible nitric oxide synthase promoter with severe malaria in Thailand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

The pathophysiologic and prognostic significance of acidosis in severe adult malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

von Willebrand factor propeptide in malaria: evidence of acute endothelial cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Beneficial effects of nitric oxide breathing in adult patients with sickle cell crisis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

A trial of artemether or quinine in children with cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Inhaled nitric oxide in acute respiratory distress syndrome: a pilot randomized controlled study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Silo-Filler's disease, the acute respiratory distress syndrome, and oxides of nitrogen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Blinded trials taken to the test: an analysis of randomized clinical trials that report tests for the success of blinding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Inhaled nitric oxide and the societal perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Cost-effectiveness of inhaled nitric oxide in the treatment of neonatal respiratory failure in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Trust and informed consent: insights from community members on the Kenyan coast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Towards a framework for community engagement in global health research

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Inhaled nitric oxide for acute hypoxemic respiratory failure in children and adults

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Obtaining informed consent in Bangladesh

16 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151218

Towards a science of community engagement

16 November 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-12-176

Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21752262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhaled nitric oxide for the early treatment of persistent pulmonary hypertension of the term newborn: a randomized, double-masked, placebo-controlled, dose-response, multicenter study. The I-NO/PPHN Study Group

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21752262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1745-6215-12-176

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

21752262