Dantrolene ameliorates the metabolic hallmarks of sepsis in rats and improves survival in a mouse model of endotoxemia (Q35151702)

6 August 2017

Dantrolene ameliorates the metabolic hallmarks of sepsis in rats and improves survival in a mouse model of endotoxemia (English)

1 reference

6 August 2017

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1 reference

R S Hotchkiss

1

1 reference

PubMed ID

8159702

6 August 2017

I E Karl

series ordinal

2

1 reference

PubMed ID

8159702

6 August 2017

language of work or name

English

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publication date

1 April 1994

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

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6 August 2017

91

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6 August 2017

8

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6 August 2017

3039-3043

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Increased intracellular Ca2+: a critical link in the pathophysiology of sepsis?

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Pathogenetic mechanisms of septic shock

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Role of intracellular calcium in NI-35-evoked collapse of neuronal growth cones.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Sepsis and septic shock--a review of laboratory models and a proposal

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

The effect of gram negative endotoxin on the calcium uptake activity of sarcoplasmic reticulum isolated from canine myocardium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Response of muscle protein turnover to insulin after acute exercise and training

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Hypermetabolism, organ failure, and metabolic support

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Influence of calcium and other divalent cations on protein turnover in rat skeletal muscle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Effect of diltiazem on altered cellular calcium regulation during endotoxic shock

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Malignant hyperthermia. Dantrolene--dynamics and kinetics

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Parathyroid hormone acutely elevates intracellular calcium in osteoblastlike cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Effect of insulin on glucose utilization in epitrochlearis muscle of rats with streptozocin-induced NIDDM.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Elevation of intracellular free calcium levels in HEp-2 cells infected with enteropathogenic Escherichia coli

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Intracellular calcium and pH alterations induced by Escherichia coli endotoxin in rat hepatocytes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Reduction in the Ca2(+)-induced Ca2+ release from canine cardiac sarcoplasmic reticulum following endotoxin administration.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Is dantrolene safe to administer in sepsis? The effect of dantrolene after endotoxin administration in dogs and rats.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Calcium-dependent and calcium-independent protease activities in skeletal muscle during sepsis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Calcium-Mediated Mechanisms in Chemically Induced Cell Death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Reevaluation of the role of cellular hypoxia and bioenergetic failure in sepsis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Low dose calcium administration increases mortality during septic peritonitis in rats.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortic

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

The relationship between the transport of glucose and cations across cell membranes in isolated tissues. IX. The role of cellular calcium in the activation of the glucose transport system in rat soleus muscle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Human sepsis increases lymphocyte intracellular calcium.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Differences in circulating gluconeogenic substrates during short-term fasting in men, women, and children.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Contribution of different organs to increased glucose consumption after endotoxin administration.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Calcium: does it have a therapeutic role in sepsis?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43510

Assessment of the role of Ca2+ mobilization from intracellular pool(s), using dantrolene, in the glycogenolytic action of alpha-adrenergic stimulation in perfused rat liver

27 September 2018

1 reference

12 December 2020

Diminution of contractile response of the aorta from endotoxin-injected rats

1 reference

12 December 2020

Differential expression of interleukin-1 and tumor necrosis factor in murine septic shock models

1 reference

12 December 2020

Dantrolene normalizes serum creatine kinase in MDX mice

1 reference

12 December 2020

Diltiazem restores IL-2, IL-3, IL-6, and IFN-γ synthesis and decreases host susceptibility to sepsis following hemorrhage

1 reference

12 December 2020

Impaired calcium uptake by cardiac sarcoplasmic reticulum and its underlying mechanism in endotoxin shock

1 reference

12 December 2020

Alanine and glutamine synthesis and release from skeletal muscle. II. The precursor role of amino acids in alanine and glutamine synthesis

1 reference

12 December 2020

Muscle proteolysis induced by a circulating peptide in patients with sepsis or trauma

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.91.8.3039

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference

PubMed ID

8159702