Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance (Q35152165)

6 August 2017

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title

Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance (English)

1 reference

6 August 2017

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3

Todd W Vanderah

1 reference

6 August 2017

4

Frank Porreca

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6 August 2017

2

Josephine Lai

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6 August 2017

1

Michael H Ossipov

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PubMed ID

12801599

6 August 2017

language of work or name

English

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publication date

1 June 2003

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6 August 2017

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6 August 2017

73

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6 August 2017

6

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6 August 2017

783-800

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Endogenous Opioids: Biology and Function

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Different mechanisms mediate development and expression of tolerance and dependence for peripheral mu-opioid antinociception in rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Hyperalgesic response in a patient receiving high concentrations of spinal morphine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Dynorphin A increases substance P release from trigeminal primary afferent C-fibers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Clinical experience of long-term treatment with epidural and intrathecal opioids--a nationwide survey

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

The role of CCK caerulein, and CCK antagonists in nociception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Sensitization of pain pathways in the spinal cord: cellular mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Delta(2)-opioid receptor mediation of morphine-induced CCK release in the frontal cortex of the freely moving rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Delta-opioid receptor-mediated increase in cortical extracellular levels of cholecystokinin-like material by subchronic morphine in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Hyperalgesia during naloxone-precipitated withdrawal from morphine is associated with increased on-cell activity in the rostral ventromedial medulla

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Effects of spinal versus supraspinal administration of cyclic nucleotide-dependent protein kinase inhibitors on morphine tolerance in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Attenuation of tolerance to opioid-induced antinociception and protection against morphine-induced decrease of neurofilament proteins by idazoxan and other I2-imidazoline ligands.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Descending facilitatory modulation of a behavioral nociceptive response by stimulation in the adult rat anterior cingulate cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Evidence for opiate-activated NMDA processes masking opiate analgesia in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Long-lasting hyperalgesia induced by fentanyl in rats: preventive effect of ketamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Progressive enhancement of delayed hyperalgesia induced by repeated heroin administration: a sensitization process

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Opioid receptor-coupled second messenger systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Neurobiological mechanisms of opioid tolerance and dependence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Influence of opiate tolerance and calcium channel antagonists on the antinociceptive effects of L-arginine and NG-nitro L-arginine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Differential release of cholecystokinin by morphine in rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Increases of CCK mRNA and peptide in different brain areas following acute and chronic administration of morphine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Reversal of tolerance to morphine but no potentiation of morphine-induced analgesia by antiserum against cholecystokinin octapeptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Enhancement of morphine analgesia and prevention of morphine tolerance in the rat by the cholecystokinin antagonist L-364,718.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

The selective CCK-B receptor antagonist L-365,260 enhances morphine analgesia and prevents morphine tolerance in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Up-regulation of opioid gene expression in spinal cord evoked by experimental nerve injuries and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Activity-dependent neuronal plasticity following tissue injury and inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Preemptive hyperalgesia, not analgesia?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Dextromethorphan shows efficacy in experimental pain (nociception) and opioid tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

The development of tolerance to morphine in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Quantitative assessment of tolerance to and dependence on morphine in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Anatomy and physiology of a nociceptive modulatory system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

The activity of neurons in the rostral medulla of the rat during withdrawal from noxious heat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Neurotransmitters in Nociceptive Modulatory Circuits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Misconceptions and controversies regarding the use of opioids in cancer pain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Trigeminal and dorsal root ganglion neurons express CCK receptor binding sites in the rat, rabbit, and monkey: possible site of opiate-CCK analgesic interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Dynorphin-(1-13), an extraordinarily potent opioid peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Beta-endorphin processing and cellular origins in rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Direct and indirect actions of morphine on medullary neurons that modulate nociception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Circuitry underlying antiopioid actions of cholecystokinin within the rostral ventromedial medulla

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Neurochemical actions of CCK underlying the therapeutic potential of CCK-B antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Cholecystokinin octapeptide excites dorsal horn neurons both in vivo and in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Hyperalgesia during acute opioid abstinence: evidence for a nociceptive facilitating function of the rostral ventromedial medulla

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Spinal co-administration of cholecystokinin antagonists with morphine prevents the development of opioid tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Morphine analgesia and acute physical dependence: rapid onset of two opposing, dose-related processes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Acute tolerance associated with a single opiate administration: involvement of N-methyl-D-aspartate-dependent pain facilitatory systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Long-lasting increased pain sensitivity in rat following exposure to heroin for the first time

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Opiate tolerance to daily heroin administration: an apparent phenomenon associated with enhanced pain sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

NMDA-receptor regulation of substance P release from primary afferent nociceptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Extracellular cholecystokinin levels in the rat spinal cord following chronic morphine exposure: an in vivo microdialysis study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Inhibition of morphine tolerance by NMDA receptor antagonists in the formalin test

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Orphanin FQ/nociceptin attenuates the development of morphine tolerance in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Continuous co-administration of dextromethorphan or MK-801 with morphine: attenuation of morphine dependence and naloxone-reversible attenuation of morphine tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Evidence for cholecystokinin-like immunoreactive neurons in the rat medulla oblongata which project to the spinal cord.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Experimental mononeuropathy reduces the antinociceptive effects of morphine: implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Increases in protein kinase C gamma immunoreactivity in the spinal cord of rats associated with tolerance to the analgesic effects of morphine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Oral administration of dextromethorphan prevents the development of morphine tolerance and dependence in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Pain facilitatory circuits in the mammalian central nervous system: their behavioral significance and role in morphine analgesic tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Alteration of calcitonin gene related peptide and its receptor binding sites during the development of tolerance to mu and delta opioids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

A calcitonin gene-related peptide receptor antagonist prevents the development of tolerance to spinal morphine analgesia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Pronounced changes in the activity of nociceptive modulatory neurons in the rostral ventromedial medulla in response to prolonged thermal noxious stimuli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Modulation of opioid antinociception by CCK at the supraspinal level: evidence of regulatory mechanisms between CCK and enkephalin systems in the control of pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Naltrindole, an opioid delta antagonist, blocks the enhancement of morphine-antinociception induced by a CCKB antagonist in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

CCK 8 analgesia and hyperalgesia after intrathecal administration in the rat: Comparison with CCK-related peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Enkephalinergic and dynorphinergic neurons in the spinal cord and dorsal root ganglia of the polyarthritic rat - in vivo release and cDNA hybridization studies.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Comparative effects of cyclo-oxygenase and nitric oxide synthase inhibition on the development and reversal of spinal opioid tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Cholecystokinin gene expression in rat amygdaloid neurons: normal distribution and effect of morphine tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Reversal of morphine tolerance and dependence by melatonin: possible role of central and peripheral benzodiazepine receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Tolerance to morphine analgesia: decreased multiplicative interaction between spinal and supraspinal sites.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Pharmacology of spinal opioids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Regional localization of the mRNA coding for the neuropeptide cholecystokinin in the rat brain studied by in situ hybridization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Modulation of the in vivo actions of morphine by the mixed CCKA/B receptor antagonist PD 142898.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Selective potentiation of NMDA-induced activity and release of excitatory amino acids by dynorphin: possible roles in paralysis and neurotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Cholecystokinin and morphine analgesia: variations on a theme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Localization and opiate receptor binding of enkephalin, CCK and ACTH/β-endorphin in the rat central nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Differential effects of sulfated cholecystokinin octapeptide and proglumide injected intrathecally on antinociception induced by beta-endorphin and morphine administered intracerebroventricularly in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Characterization of biphasic modulation of spinal nociceptive transmission by neurotensin in the rat rostral ventromedial medulla

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Antisense oligodeoxynucleotide to the CCKB receptor produces naltrindole- and [Leu5]enkephalin antiserum-sensitive enhancement of morphine antinociception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Cholecystokinin in mammalian primary sensory neurons and spinal cord: in situ hybridization studies in rat and monkey

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Pre-emptive dynorphin and N-methyl-D-aspartate glutamate receptor antagonism alters spinal immunocytochemistry but not allodynia following complete peripheral nerve injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Spinal dynorphin immunoreactivity increases bilaterally in a neuropathic pain model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Pronociceptive actions of dynorphin maintain chronic neuropathic pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Cholecystokinin antagonists selectively potentiate analgesia induced by endogenous opiates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

The role of cholecystokinin in nociception, neuropathic pain and opiate tolerance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Intrathecal high dose morphine produces hyperalgesia in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

CI988, a selective antagonist of cholecystokininB receptors, prevents morphine tolerance in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Induction of tolerance and withdrawal in rats receiving morphine in the spinal subarachnoid space

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

High dose of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: clinical and theoretic implications.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Increased release of immunoreactive cholecystokinin octapeptide by morphine and potentiation of mu-opioid analgesia by CCKB receptor antagonist L-365,260 in rat spinal cord

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Characterization of descending inhibition and facilitation from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Characterization of descending facilitation and inhibition of spinal nociceptive transmission from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

Biphasic modulation of spinal nociceptive transmission from the medullary raphe nuclei in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0024-3205%2803%2900410-7

10.1016/S0024-3205(03)00410-7

7 January 2021

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12801599