Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver (Q35152192)

6 August 2017

Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver (English)

1 reference

6 August 2017

Eun-Jeong Jung

1

1 reference

6 August 2017

Sung-Won Kwon

2

1 reference

6 August 2017

Byung-Hwa Jung

3

1 reference

6 August 2017

Seon-Hee Oh

4

1 reference

6 August 2017

Byung-Hoon Lee

5

1 reference

6 August 2017

14 July 2011

1 reference

Journal of Lipid Research

6 August 2017

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6 August 2017

52

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6 August 2017

9

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6 August 2017

1617-1625

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N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRalpha

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Second-hand smoke stimulates lipid accumulation in the liver by modulating AMPK and SREBP-1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Expression of lipogenic factors galectin-12, resistin, SREBP-1, and SCD in human sebaceous glands and cultured sebocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

The role of AMP-activated protein kinase in the action of ethanol in the liver

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Induction of CYP1A1 in primary rat hepatocytes by 3,3',4,4',5-pentachlorobiphenyl: evidence for a switch circuit element

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

mTOR Signaling to Translation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Role of AMP-activated protein kinase in mechanism of metformin action

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

The regulation of AMP-activated protein kinase by phosphorylation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Ribosomal S6 kinase signaling and the control of translation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Regulation of lipid metabolism by the AMP-activated protein kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Decreased secretion of very-low-density lipoprotein triacylglycerol and apolipoprotein B is associated with decreased intracellular triacylglycerol lipolysis in hepatocytes derived from rats fed orotic acid or n-3 fatty acids

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Control of p70 s6 kinase by kinase activity of FRAP in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Single-run high-performance liquid chromatography of nucleotides, nucleosides, and major purine bases and its application to different tissue extracts.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Fenofibrate prevents orotic acid--induced hepatic steatosis in rats.

13 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

Dietary phosphatidylcholine alleviates fatty liver induced by orotic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

Expansion and redifferentiation of adult human pancreatic islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M015263

Species specificity in the metabolic consequences of orotic acid consumption.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3151682

Species Specificity of Arginine Deficiency-Induced Hepatic Steatosis

27 September 2018

1 reference

12 December 2020

Is cigarette smoking an independent risk factor or a cofactor for nonalcoholic fatty liver disease?

1 reference

12 December 2020

Mechanisms underlying impaired GLUT-4 translocation in glycogen-supercompensated muscles of exercised rats

1 reference

12 December 2020

Effects of orotic acid on purine and lipoprotein metabolism in man

1 reference

12 December 2020

Reduction of beta-oxidation capacity of rat liver mitochondria by feeding orotic acid

1 reference

12 December 2020

Cardioprotection by orotic acid: metabolism and mechanism of action

1 reference

12 December 2020

Nucleotide metabolism. I. The conversion of orotic acid-6-C14 to uridine nucleotides

1 reference

12 December 2020

Fatty livers induced by orotic acid. I. Accumulation and metabolism of lipids

1 reference

12 December 2020

Fatty liver induced by orotic acid feeding

1 reference

12 December 2020

Increased expression of sonic hedgehog and altered methylation of its promoter region in gastric cancer and its related lesions

1 reference

12 December 2020

Activation of mammalian target of rapamycin complex 1 and insulin resistance induced by palmitate in hepatocytes.

1 reference

12 December 2020

Oxidative stress induced lipid accumulation via SREBP1c activation in HepG2 cells

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M015263

1 reference

6 August 2017

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6 August 2017

1 reference