The role of mitochondrial DNA mutation on neurodegenerative diseases (Q35152954)

6 August 2017

7 references

25 April 2019

20 June 2019

30 June 2019

2 August 2019

14 September 2019

20 September 2020

6 November 2020

The role of mitochondrial DNA mutation on neurodegenerative diseases (English)

1 reference

6 August 2017

1 reference

20 September 2020

5 references

25 April 2019

20 June 2019

30 June 2019

2 August 2019

14 September 2019

1 reference

2 August 2019

1 reference

14 September 2019

1 reference

6 November 2020

3

Inhee Mook-Jung

1 reference

6 August 2017

Moon-Yong Cha

1

1 reference

PubMed ID

25766619

6 August 2017

Dong Kyu Kim

series ordinal

2

1 reference

PubMed ID

25766619

6 August 2017

language of work or name

1 reference

13 March 2015

8 references

Experimental and Molecular Medicine

6 August 2017

25 April 2019

20 June 2019

30 June 2019

2 August 2019

14 September 2019

20 September 2020

6 November 2020

8 references

6 August 2017

25 April 2019

20 June 2019

30 June 2019

2 August 2019

14 September 2019

20 September 2020

6 November 2020

47

1 reference

6 August 2017

e150

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

6 August 2017

7 references

25 April 2019

20 June 2019

30 June 2019

2 August 2019

14 September 2019

20 September 2020

on focus list of Wikimedia project

6 November 2020

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/emm.2014.122

0 references

cites work

CR6-interacting factor 1 is a key regulator in Aβ-induced mitochondrial disruption and pathogenesis of Alzheimer's disease

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Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system

28 July 2018

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Modeling of antigenomic therapy of mitochondrial diseases by mitochondrially addressed RNA targeting a pathogenic point mutation in mitochondrial DNA

28 July 2018

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Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations

28 July 2018

1 reference

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28 July 2018

1 reference

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Base excision DNA repair levels in mitochondrial lysates of Alzheimer's disease

28 July 2018

1 reference

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Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease

28 July 2018

1 reference

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Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

28 July 2018

1 reference

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Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity

28 July 2018

1 reference

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The Alzheimer's disease mitochondrial cascade hypothesis: progress and perspectives

28 July 2018

1 reference

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Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes

28 July 2018

1 reference

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Ambiguities in NLRP3 inflammasome regulation: is there a role for mitochondria?

28 July 2018

1 reference

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Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs

28 July 2018

1 reference

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28 July 2018

The hallmarks of aging

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Pharmacological approaches to restore mitochondrial function

28 July 2018

1 reference

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Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models

28 July 2018

1 reference

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Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis

28 July 2018

1 reference

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The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation

28 July 2018

1 reference

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Autophagosomes form at ER-mitochondria contact sites

28 July 2018

1 reference

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The role of mitochondrial DNA mutations and free radicals in disease and ageing

28 July 2018

1 reference

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Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease

28 July 2018

1 reference

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Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease

28 July 2018

1 reference

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Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

28 July 2018

1 reference

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Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria, oxidative stress and neurodegeneration.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria and cardiovascular aging

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's disease

28 July 2018

1 reference

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Mitochondria and the autophagy-inflammation-cell death axis in organismal aging

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

The human mitochondrial transcriptome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria, Amyloid β, and Alzheimer's Disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Could successful (mitochondrial) networking help prevent Huntington's disease?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial fusion and fission in cell life and death

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

The sites and topology of mitochondrial superoxide production

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Reactive oxygen species, cellular redox systems, and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Functional organization of mammalian mitochondrial DNA in nucleoids: history, recent developments, and future challenges.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

The coordination of nuclear and mitochondrial communication during aging and calorie restriction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial DNA mutations in disease, aging, and neurodegeneration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial fragmentation in neurodegeneration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial dynamics and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Genome-wide responses to mitochondrial dysfunction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Sequence and organization of the human mitochondrial genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

An update on the mitochondrial-DNA mutation hypothesis of cell aging

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria-targeted Ogg1 and aconitase-2 prevent oxidant-induced mitochondrial DNA damage in alveolar epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM)

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial pharmacology

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Sensing and reacting to microbes through the inflammasomes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial DNA deletions cause the biochemical defect observed in Alzheimer's disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondria breathe for autophagy

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM).

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Mitochondrial abnormalities in Alzheimer's disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4351410

Coordinate induction of energy gene expression in tissues of mitochondrial disease patients

27 September 2018

1 reference

12 December 2020

Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles

1 reference

12 December 2020

Mitochondrial dysfunction in Parkinson's disease

1 reference

12 December 2020

Mitochondrial DNA deletion mutation levels are elevated in ALS brains

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMM.2014.122

1 reference

release_i4oqcfh75jfufepbtyhwpjvkte

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/i4oqcfh75jfufepbtyhwpjvkte

24 November 2022

mapped directly with Wikidata item

PMCID

4351410

1 reference

6 August 2017

1 reference

PubMed ID

25766619