Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo (Q35156294)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20422624%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo (English)

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1 February 2020

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8

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1 February 2020

Michael J. Rogers

13

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1 February 2020

author name string

Anke J Roelofs

1

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1 February 2020

Fraser P Coxon

2

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1 February 2020

Frank H Ebetino

3

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1 February 2020

Mark W Lundy

4

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1 February 2020

Zachary J Henneman

5

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1 February 2020

George H Nancollas

6

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1 February 2020

Shuting Sun

7

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1 February 2020

Joy Lynn F Bala

9

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1 February 2020

Boris A Kashemirov

10

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1 February 2020

Aysha B Khalid

11

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1 February 2020

Charles E McKenna

12

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publication date

1 March 2010

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Journal of Bone and Mineral Research

1 February 2020

published in

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1 February 2020

volume

25

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1 February 2020

issue

3

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1 February 2020

page(s)

606-616

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Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.

1 February 2020

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Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo

13 July 2018

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Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma

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Bisphosphonate binding affinity as assessed by inhibition of carbonated apatite dissolution in vitro

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Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases.

13 July 2018

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The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

13 July 2018

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Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis

13 July 2018

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The bisphosphonate acute phase response: rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins

13 July 2018

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Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling

13 July 2018

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An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

13 July 2018

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Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells

13 July 2018

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Transduction of cell survival signals by connexin-43 hemichannels

13 July 2018

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In vivo near-infrared fluorescence imaging of osteoblastic activity

13 July 2018

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Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

13 July 2018

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Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

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Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

13 July 2018

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Migration and phenotypic transformation of osteoclast precursors into mature osteoclasts: the effect of a bisphosphonate.

13 July 2018

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13 July 2018

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13 July 2018

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Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.

27 September 2018

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Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite

27 September 2018

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Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo

27 September 2018

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27 September 2018

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Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: the role of protein geranylgeranylation in the action of nitrogen-containing bisphosphona

27 September 2018

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Stimulation of gammadelta T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma

27 September 2018

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12 December 2020

Isolation and Purification of Rabbit Osteoclasts

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12 December 2020

Alendronate distributed on bone surfaces inhibits osteoclastic bone resorption in vitro and in experimental hypercalcemia models

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12 December 2020

Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones

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12 December 2020

Identifiers

DOI

10.1359/JBMR.091009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20422624%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20422624%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference