HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis. (Q35157022)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691750%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis (English)

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1 March 2020

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0 references

1 reference

Guohua Wang

1

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Yejie Shi

2

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1 March 2020

Xiaoyan Jiang

3

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Xiaoming Hu

5

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Yun Wu

6

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Hongjian Pu

7

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Wei-Wei Li

8

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Bo Tang

9

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1 March 2020

Yun Wang

10

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Yanqin Gao

11

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Ping Zheng

12

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1 March 2020

Michael V L Bennett

13

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1 March 2020

language of work or name

English

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publication date

17 February 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691750%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

1 March 2020

published in

1 reference

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volume

112

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1 March 2020

issue

9

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1 March 2020

page(s)

2853-2858

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Microglial and macrophage polarization—new prospects for brain repair

1 March 2020

cites work

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Inflammation and white matter degeneration persist for years after a single traumatic brain injury

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Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT.

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Temporal changes in cell marker expression and cellular infiltration in a controlled cortical impact model in adult male C57BL/6 mice

13 July 2018

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Valproic acid increases white matter repair and neurogenesis after stroke

13 July 2018

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13 July 2018

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Prognostic value of diffusion tensor imaging parameters in severe traumatic brain injury.

13 July 2018

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Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in rats.

13 July 2018

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13 July 2018

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Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

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Role of microglia in neurotrauma

13 July 2018

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Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats

13 July 2018

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Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury

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HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats

13 July 2018

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13 July 2018

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

13 July 2018

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27 September 2018

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27 September 2018

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27 September 2018

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Putting the 'HAT' back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25691750

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12 December 2020

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Identifiers

DOI

10.1073/PNAS.1501441112

1 reference

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1 March 2020

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24 November 2022

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1 March 2020

PubMed publication ID

25691750

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