BMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs (Q35157807)

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English	BMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

BMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Akihiko Hiyama

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Shilpa S Gogate

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Sachin Gajghate

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Joji Mochida

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Irving M Shapiro

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Makarand V Risbud

6

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Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

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publication date

1 May 2010

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Europe PubMed Central

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6 August 2017

Journal of Bone and Mineral Research

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Europe PubMed Central

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6 August 2017

25

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Europe PubMed Central

PubMed publication ID

6 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1179-1190

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc

1 reference

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Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation

1 reference

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Oxidized low-density lipoprotein induces matrix metalloproteinase-9 expression via a p42/p44 and JNK-dependent AP-1 pathway in brain astrocytes.

1 reference

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The effects of recombinant human bone morphogenetic protein-2, recombinant human bone morphogenetic protein-12, and adenoviral bone morphogenetic protein-12 on matrix synthesis in human annulus fibrosis and nucleus pulposus cells

1 reference

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13 July 2018

MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38delta

1 reference

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13 July 2018

Calcineurin-NFATc signaling pathway regulates AQP2 expression in response to calcium signals and osmotic stress

1 reference

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13 July 2018

Downregulation of cAMP-dependent protein kinase inhibitor gamma is required for BMP-2-induced osteoblastic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153993

13 July 2018

Evidence of calcium-dependent pathway in the regulation of human beta1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis

1 reference

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How tonicity regulates genes: story of TonEBP transcriptional activator

1 reference

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13 July 2018

Mechanobiology of the intervertebral disc and relevance to disc degeneration

1 reference

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13 July 2018

Extracellular matrix in disc degeneration

1 reference

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Involvement of JNKs and p38-MAPK/MSK1 pathways in H2O2-induced upregulation of heme oxygenase-1 mRNA in H9c2 cells

1 reference

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13 July 2018

Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair

1 reference

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13 July 2018

The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1

1 reference

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13 July 2018

Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153993

13 July 2018

Interleukin-1beta down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1beta-mediated effects in rat chondrocytes

1 reference

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13 July 2018

The NFAT-related protein NFATL1 (TonEBP/NFAT5) is induced upon T cell activation in a calcineurin-dependent manner

1 reference

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13 July 2018

Chinese hamster ovary cell mutants defective in glycosaminoglycan assembly and glucuronosyltransferase I.

1 reference

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Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate

1 reference

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13 July 2018

Developmental changes in serum UDP-GlcA:chondroitin glucuronyltransferase activity.

1 reference

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13 July 2018

Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153993

27 September 2018

Toward an optimum system for intervertebral disc organ culture: TGF-beta 3 enhances nucleus pulposus and anulus fibrosus survival and function through modulation of TGF-beta-R expression and ERK signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153993

27 September 2018

Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153993

27 September 2018

Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3153993

27 September 2018

Osmotic response element-binding protein (OREBP) is an essential regulator of the urine concentrating mechanism.

1 reference

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In vivo growth factor treatment of degenerated intervertebral discs

1 reference

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Individual cartilage aggrecan macromolecules and their constituent glycosaminoglycans visualized via atomic force microscopy.

1 reference

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27 September 2018

Effect of bone morphogenetic protein-2 (BMP-2) on matrix production, other BMPs, and BMP receptors in rat intervertebral disc cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19961337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc

1 reference

https://pubmed.ncbi.nlm.nih.gov/19961337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta1 calcium signaling in osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19961337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/OREBP

1 reference

https://pubmed.ncbi.nlm.nih.gov/19961337

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1359/JBMR.091202

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

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