Levosimendan restores the positive force-frequency relation in heart failure (Q35159849)

6 August 2017

Levosimendan restores the positive force-frequency relation in heart failure (English)

1 reference

6 August 2017

Satoshi Masutani

1

1 reference

6 August 2017

Heng-Jie Cheng

2

1 reference

6 August 2017

Hideo Tachibana

3

1 reference

6 August 2017

William C Little

4

1 reference

6 August 2017

Che-Ping Cheng

5

1 reference

6 August 2017

13 May 2011

1 reference

American Journal of Physiology Heart and Circulatory Physiology

6 August 2017

1 reference

6 August 2017

301

1 reference

6 August 2017

2

1 reference

6 August 2017

H488-96

1 reference

Usefulness of heart rate at rest as a predictor of mortality, hospitalization for heart failure, myocardial infarction, and stroke in patients with stable coronary heart disease (Data from the Treating to New Targets [TNT] trial).

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

The utility of levosimendan in the treatment of heart failure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Evidence-based use of levosimendan in different clinical settings

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Mechanisms and use of calcium-sensitizing agents in the failing heart

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Force-frequency relationship in intact mammalian ventricular myocardium: physiological and pathophysiological relevance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Mechanisms of action of novel cardiotonic agents

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Myocardial efficiency during levosimendan infusion in congestive heart failure.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

beta-adrenergic receptor blockade in chronic heart failure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Force-frequency relation in patients with left ventricular hypertrophy and failure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Effects of levosimendan on myocardial contractility and Ca2+ transients in aequorin-loaded right-ventricular papillary muscles and indo-1-loaded single ventricular cardiomyocytes of the rabbit

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Mechanisms of action of calcium-sensitizing drugs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Troponin C-mediated calcium sensitization induced by levosimendan does not impair relaxation.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Left ventricular interaction with arterial load studied in isolated canine ventricle.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Alterations in the baroreceptor reflex in conscious dogs with heart failure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

The left ventricular dP/dtmax-end-diastolic volume relation in closed-chest dogs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Efficiency of energy transfer from pressure-volume area to external mechanical work increases with contractile state and decreases with afterload in the left ventricle of the anesthetized closed-chest dog

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Orally available levosimendan dose-related positive inotropic and lusitropic effect in conscious chronically instrumented normal and heart failure dogs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Effects of levosimendan on restrictive left ventricular filling in severe heart failure: a combined hemodynamic and Doppler echocardiographic study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

The Ca2+-sensitizer levosimendan improves oxidative damage, BNP and pro-inflammatory cytokine levels in patients with advanced decompensated heart failure in comparison to dobutamine

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Pharmacokinetics of levosimendan and its active metabolite OR-1896 in rapid and slow acetylators

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Levosimendan improves LV systolic and diastolic performance at rest and during exercise after heart failure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Endogenous beta3-adrenoreceptor activation contributes to left ventricular and cardiomyocyte dysfunction in heart failure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Pharmacokinetic-pharmacodynamic interrelationships of intravenous and oral levosimendan in patients with severe congestive heart failure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Sustained hemodynamic effects of intravenous levosimendan

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN).

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Beneficial effects of the Ca(2+) sensitizer levosimendan in human myocardium

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

The role of ANG II and endothelin-1 in exercise-induced diastolic dysfunction in heart failure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Levosimendan improves diastolic and systolic function in failing human myocardium.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Influence of the novel inotropic agent levosimendan on isometric tension and calcium cycling in failing human myocardium.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

The novel calcium sensitizer levosimendan activates the ATP-sensitive K+ channel in rat ventricular cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Systemic and coronary hemodynamic actions and left ventricular functional effects of levosimendan in conscious dogs.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3154658

Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1152%2FAJPHEART.01116.2010

Influence of heart rate on left ventricular performance in conscious dogs

21 January 2018

1 reference

12 December 2020

Influence of the force-frequency relation on left ventricular function during exercise in conscious dogs

1 reference

12 December 2020

Haemodynamic and neurohumoral response in heart failure produced by rapid ventricular pacing

1 reference

12 December 2020

Effect of exercise on left ventricular-arterial coupling assessed in the pressure-volume plane

1 reference

12 December 2020

Report of the Task Force on Research in Heart Failure

1 reference

12 December 2020

Effect of exercise on left ventricular mechanical efficiency in conscious dogs

1 reference

12 December 2020

Effects of Levosimendan, a cardiotonic agent targeted to troponin C, on cardiac function and on phosphorylation and Ca2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart

1 reference

12 December 2020

Effects of EMD 57033 on Contraction and Relaxation in Isolated Rabbit Hearts

1 reference

12 December 2020

Altered ventricular and myocyte response to angiotensin II in pacing-induced heart failure

1 reference

12 December 2020

Effects of levosimendan on myocardial contractility and oxygen consumption

1 reference

12 December 2020

Levosimendan enhances left ventricular systolic and diastolic function in conscious dogs with pacing-induced cardiomyopathy

1 reference

12 December 2020

Effect of cyclopiazonic acid on the force-frequency relationship in human nonfailing myocardium

1 reference

12 December 2020

Adrenergic control of the force-frequency and relaxation-frequency relations in patients with hypertrophic cardiomyopathy

1 reference

12 December 2020

Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects

1 reference

12 December 2020

Effect of inotropic interventions on the force-frequency relation in the human heart

1 reference

12 December 2020

Effects of atrial natriuretic peptide on left ventricular performance in conscious dogs before and after pacing-induced heart failure

1 reference

12 December 2020

Sarcoplasmic reticulum and nuclear envelope are one highly interconnected Ca2+ store throughout cardiac myocyte

1 reference

12 December 2020

Direct myocardial effects of levosimendan in humans with left ventricular dysfunction: alteration of force-frequency and relaxation-frequency relationships

1 reference

12 December 2020

Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity

1 reference

12 December 2020

Restrictive left ventricular filling pattern does not result from increased left atrial pressure alone

1 reference

12 December 2020

Tachycardia exacerbates abnormal left ventricular-arterial coupling in heart failure

1 reference

12 December 2020

10.1152/AJPHEART.01116.2010

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference