Eosinophils generate brominating oxidants in allergen-induced asthma (Q35160027)

6 August 2017

Eosinophils generate brominating oxidants in allergen-induced asthma (English)

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6 August 2017

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4

M J Thomassen

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6 August 2017

W Wu

1

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6 August 2017

M K Samoszuk

2

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6 August 2017

S A Comhair

3

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6 August 2017

C F Farver

5

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6 August 2017

R A Dweik

6

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6 August 2017

M S Kavuru

7

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6 August 2017

S C Erzurum

8

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6 August 2017

S L Hazen

9

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6 August 2017

language of work or name

English

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publication date

1 May 2000

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Journal of Clinical Investigation

6 August 2017

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6 August 2017

105

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6 August 2017

10

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6 August 2017

1455-1463

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The role of allergy in the development of asthma

6 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Thiocyanate and chloride as competing substrates for myeloperoxidase.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Human neutrophils employ chlorine gas as an oxidant during phagocytosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Effects of sonicated eosinophils on the in vitro sensitivity of human lymphoma cells to glucose oxidase.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Role of cell-generated hydrogen peroxide in granulocyte-mediated killing of schistosomula of Schistosoma mansoni in vitro

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Synthesis of brominated heptanones and bromoform by a bromoperoxidase of marine origin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Bactericidal activity of eosinophil peroxidase.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Oxidative Response of Phagocytes to Parasite Invasion

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Some enzymatic characteristics of eosinophil peroxidase from patients with eosinophilia and from healthy donors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Human eosinophil peroxidase: purification and characterization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Extensive deposition of eosinophil peroxidase in Hodgkin's and non-Hodgkin's lymphomas

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Brominating oxidants generated by human eosinophils

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Comparative toxicity of the horse eosinophil peroxidase-H2O2-halide system and granule basic proteins.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Eosinophils and human disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Molecular cloning and characterization of a chromosomal gene for human eosinophil peroxidase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Eosinophils preferentially use bromide to generate halogenating agents

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Thiocyanate is the major substrate for eosinophil peroxidase in physiologic fluids. Implications for cytotoxicity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Bromide-dependent toxicity of eosinophil peroxidase for endothelium and isolated working rat hearts: a model for eosinophilic endocarditis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Tumor necrosis factor alpha/cachectin stimulates eosinophil oxidant production and toxicity towards human endothelium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Two new brominated tyrosine derivatives from the sponge Druinella (= Psammaplysilla) purpurea

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Inflammatory cells and eicosanoid mediators in subjects with late asthmatic responses and increases in airway responsiveness

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Fistularin 3 and 11-ketofistularin 3. Feline leukemia virus active bromotyrosine metabolites from the marine sponge Aplysina archeri

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Oxidative metabolism of the human eosinophil

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Study on the superoxide-producing enzyme of eosinophils and neutrophils--comparison of the NADPH oxidase components

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Eosinophils increase lung microvascular permeability via the peroxidase-hydrogen peroxide-halide system. Bronchoconstriction and vasoconstriction unaffected by eosinophil peroxidase inhibition.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Effects of activated eosinophils cultured from human umbilical cord blood on guinea pig trachealis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Eosinophil-mediated mammalian tumor cell cytotoxicity: role of the peroxidase system.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Peroxidase-mediated toxicity to schistosomula of Schistosoma mansoni

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=315470

Synthesis and microbiological activities of some monohalogenated analogs of tyrosine

27 September 2018

1 reference

12 December 2020

Eosinophil autofluorescence and its use in isolation and analysis of human eosinophils using flow microfluorometry

1 reference

12 December 2020

Assessment of chlorination by human neutrophils

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12 December 2020

Identification of eosinophils by flow cytometry

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12 December 2020

Effect of eosinophil peroxidase on airway epithelial permeability in the guinea pig

1 reference

12 December 2020

The immediate and late allergic response to segmental bronchopulmonary provocation in asthma

1 reference

12 December 2020

Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation

1 reference

12 December 2020

Marine natural products

1 reference

12 December 2020

Modification of proteins and lipids by myeloperoxidase

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12 December 2020

Protein bromination by bromoperoxidase from Penicillus capitatus

1 reference

12 December 2020

The injurious effect of eosinophil peroxidase, hydrogen peroxide, and halides on pneumocytes in vitro

1 reference

12 December 2020

Deposition of autofluorescent eosinophil granules in pathologic bone marrow biopsies

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12 December 2020

Singlet oxygen production by human eosinophils

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12 December 2020

Purification of human blood eosinophils by negative selection using immunomagnetic beads

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12 December 2020

Bromine derivatives of amino acids as intermediates in the peroxidase-catalyzed formation of singlet oxygen

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12 December 2020

Comparison of airway and blood eosinophil function after in vivo antigen challenge

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12 December 2020

Verongamine, a novel bromotyrosine-derived histamine H3-antagonist from the marine sponge Verongula gigantea

1 reference

12 December 2020

Role of eosinophil activation in the bronchial reactivity of allergic guinea pigs

1 reference

12 December 2020

Eosinophil granule proteins increase microvascular macromolecular transport in the hamster cheek pouch

1 reference

12 December 2020

Oxidation of bromide by the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase. Formation of bromamines

1 reference

12 December 2020

Spontaneous oxygen radical production at sites of antigen challenge in allergic subjects

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12 December 2020

Biosynthesis of brominated tyrosine metabolites by Aplysina fistularis

1 reference

12 December 2020

p-Hydroxyphenylacetaldehyde is the major product of L-tyrosine oxidation by activated human phagocytes. A chloride-dependent mechanism for the conversion of free amino acids into reactive aldehydes by myeloperoxidase

1 reference

12 December 2020

Nitric oxide regulation of asthmatic airway inflammation with segmental allergen challenge

1 reference

12 December 2020

Rapid loss of superoxide dismutase activity during antigen-induced asthmatic response

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12 December 2020

Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues

1 reference

12 December 2020

3-Bromotyrosine and 3,5-dibromotyrosine are major products of protein oxidation by eosinophil peroxidase: potential markers for eosinophil-dependent tissue injury in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI9702

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6 August 2017

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6 August 2017

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