Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification (Q35160736)

6 August 2017

Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification (English)

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6 August 2017

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17

Guido Kroemer

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Tobias Eisenberg

Tobias Eisenberg

11

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Sabrina Büttner

Sabrina Büttner

12

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Didac Carmona-Gutierrez

4

Didac Carmona-Gutierrez

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6 August 2017

15

Pidder Jansen-Dürr

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6 August 2017

Christoph Ruckenstuhl

1

Christoph Ruckenstuhl

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6 August 2017

2

Christine Netzberger

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6 August 2017

16

Kai-Uwe Fröhlich

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6 August 2017

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Rafal Koziel

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6 August 2017

Iryna Entfellner

3

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6 August 2017

Thomas Kickenweiz

5

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6 August 2017

Slaven Stekovic

6

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6 August 2017

Christina Gleixner

7

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6 August 2017

Christian Schmid

8

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6 August 2017

Lisa Klug

9

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6 August 2017

Alice G Sorgo

10

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6 August 2017

Guillermo Mariño

13

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6 August 2017

Frank Madeo

18

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6 August 2017

1 May 2014

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10

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e1004347

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Creative Commons Attribution 4.0 International

6 August 2017

start time

1 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan

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Sulfur amino acids regulate translational capacity and metabolic homeostasis through modulation of tRNA thiolation

28 July 2018

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Methionine inhibits autophagy and promotes growth by inducing the SAM-responsive methylation of PP2A

28 July 2018

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Dietary restriction depends on nutrient composition to extend chronological lifespan in budding yeast Saccharomyces cerevisiae

28 July 2018

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Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast.

28 July 2018

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An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

28 July 2018

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28 July 2018

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Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function

28 July 2018

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Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

28 July 2018

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Can autophagy promote longevity?

28 July 2018

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A microarray-based genetic screen for yeast chronological aging factors

28 July 2018

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Forty percent methionine restriction decreases mitochondrial oxygen radical production and leak at complex I during forward electron flow and lowers oxidative damage to proteins and mitochondrial DNA in rat kidney and brain mitochondria.

28 July 2018

1 reference

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Induction of autophagy by spermidine promotes longevity

28 July 2018

1 reference

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Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart.

28 July 2018

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Autophagy is required for extension of yeast chronological life span by rapamycin

28 July 2018

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A molecular mechanism of chronological aging in yeast.

28 July 2018

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Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae

28 July 2018

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Autophagy in the Pathogenesis of Disease

28 July 2018

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Autophagy: from phenomenology to molecular understanding in less than a decade

28 July 2018

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Depletion of endonuclease G selectively kills polyploid cells

28 July 2018

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Extension of chronological life span in yeast by decreased TOR pathway signaling

28 July 2018

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A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes

28 July 2018

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28 July 2018

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A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast

28 July 2018

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Molecular dissection of autophagy: two ubiquitin-like systems

28 July 2018

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Metabolism of sulfur amino acids in Saccharomyces cerevisiae

28 July 2018

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VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H+-ATPase assembly

28 July 2018

1 reference

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A new efficient gene disruption cassette for repeated use in budding yeast

28 July 2018

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Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo

28 July 2018

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Low methionine ingestion by rats extends life span

28 July 2018

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Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure

28 July 2018

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Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar H(+)-adenosine triphosphatase

28 July 2018

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Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae

28 July 2018

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Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

28 July 2018

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Chemical genetic screen in fission yeast reveals roles for vacuolar acidification, mitochondrial fission, and cellular GMP levels in lifespan extension.

28 July 2018

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Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling

27 September 2018

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Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction

27 September 2018

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The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006742

Lowered methionine ingestion as responsible for the decrease in rodent mitochondrial oxidative stress in protein and dietary restriction possible implications for humans.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006742

The long physiological reach of the yeast vacuolar H+-ATPase

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006742

Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006742

The effects of p53 on whole organism longevity are mediated by autophagy

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006742

Acidification of vacuoles is required for autophagic degradation in the yeast, Saccharomyces cerevisiae

27 September 2018

1 reference

12 December 2020

Chapter 3 The Quantitative Pho8Δ60 Assay of Nonspecific Autophagy

1 reference

12 December 2020

Hitchhikers guide to the vacuole-mechanisms of cargo sequestration in the Cvt and autophagic pathways

1 reference

12 December 2020

Methionine restriction decreases mitochondrial oxygen radical generation and leak as well as oxidative damage to mitochondrial DNA and proteins

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1004347

Identifiers

DOI

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6 August 2017

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6 August 2017

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