Ammonia neurotoxicity: role of the mitochondrial permeability transition (Q35161011)

6 August 2017

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title

Ammonia neurotoxicity: role of the mitochondrial permeability transition (English)

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6 August 2017

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Rama Rao KV

1

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6 August 2017

Jayakumar AR

series ordinal

2

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6 August 2017

Norenberg DM

series ordinal

3

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6 August 2017

1 June 2003

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6 August 2017

Metabolic Brain Disease

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6 August 2017

18

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6 August 2017

2

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6 August 2017

113-127

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https://scigraph.springernature.com/pub.10.1023/a:1023858902184

6 August 2017

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Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis.

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Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats

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Hyperammonaemia does not impair brain function in the absence of net glutamine synthesis

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Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells

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Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.

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Neurosteroids: endogenous bimodal modulators of the GABAA receptor. Mechanism of action and physiological significance

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Ammonia and manganese increase arginine uptake in cultured astrocytes.

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Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication.

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12 December 2020

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12 December 2020

Aspartate aminotransferase, malate dehydrogenase, and pyruvate carboxylase activities in rat cerebral synaptic and nonsynaptic mitochondria: effects of in vitro treatment with ammonia, hyperammonemia and hepatic encephalopathy.

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12 December 2020

Pyruvate decarboxylation in astrocytes and in neurons in primary cultures in the presence and the absence of ammonia.

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12 December 2020

Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy.

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12 December 2020

Nitroarginine, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication.

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12 December 2020

Hepatic encephalopathy: An update of pathophysiologic mechanisms

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12 December 2020

The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure

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12 December 2020

Tripartite synapses: glia, the unacknowledged partner

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12 December 2020

Mechanisms by which mitochondria transport calcium

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12 December 2020

Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts

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12 December 2020

Pathogenesis of hepatic encephalopathy

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12 December 2020

Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria.

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12 December 2020

Induction of permeability transition and swelling of rat brain mitochondria by glutamine

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12 December 2020

Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo

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12 December 2020

Electron microscopic evaluation of brain edema in rabbits with galactosamine-induced fulminant hepatic failure: ultrastructure and integrity of the blood-brain barrier.

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Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors

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12 December 2020

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12 December 2020

Morphologic effects of ammonia on primary astrocyte cultures. I. Light microscopic studies

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12 December 2020

Activities of pyruvate dehydrogenase, enzymes of citric acid cycle, and aminotransferases in the subcellular fractions of cerebral cortex in normal and hyperammonemic rats.

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12 December 2020

Identifiers

DOI

10.1023/A:1023858902184

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Dimensions Publication ID

6 August 2017

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