Flow NMR applications in combinatorial chemistry (Q35162426)

6 August 2017

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title

Flow NMR applications in combinatorial chemistry (English)

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6 August 2017

Paul A Keifer

1

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6 August 2017

1 June 2003

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Current Opinion in Chemical Biology

6 August 2017

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6 August 2017

7

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6 August 2017

3

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6 August 2017

388-394

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On-line liquid chromatography coupled with high field NMR and mass spectrometry (LC-NMR-MS): a new technique for drug metabolite structure elucidation

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900051-6

7 January 2021

Direct-injection NMR (DI-NMR): a flow NMR technique for the analysis of combinatorial chemistry libraries

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https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900051-6

7 January 2021

Development of a system to evaluate compound identity, purity, and concentration in a single experiment and its application in quality assessment of combinatorial libraries and screening hits

1 reference

https://api.crossref.org/works/10.1016%2FS1367-5931%2803%2900051-6

7 January 2021

Application of liquid chromatography-nuclear magnetic resonance spectroscopy to the identification of natural products

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7 January 2021

Combination of matrix solid-phase dispersion extraction and direct on-line liquid chromatography-nuclear magnetic resonance spectroscopy-tandem mass spectrometry as a new efficient approach for the rapid screening of natural products: application to

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7 January 2021

Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development

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7 January 2021

HPLC analysis of ecdysteroids in plant extracts using superheated deuterium oxide with multiple on-line spectroscopic analysis (UV, IR, 1H NMR, and MS).

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7 January 2021

Reversed-phase high-performance liquid chromatography combined with on-line UV diode array, FT infrared, and 1H nuclear magnetic resonance spectroscopy and time-of-flight mass spectrometry: application to a mixture of nonsteroidal antiinflammatory d

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7 January 2021

Application of directly coupled LC–NMR–MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83

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7 January 2021

Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography–mass spectrometry–nuclear magnetic resonance spectroscopy

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7 January 2021

Multiple hyphenation of liquid chromatography with nuclear magnetic resonance spectroscopy, mass spectrometry and beyond

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7 January 2021

Use of directly coupled ion-exchange liquid chromatography-mass spectrometry and liquid chromatography-nuclear magnetic resonance spectroscopy as a strategy for polar metabolite identification

1 reference

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7 January 2021

Flow injection analysis with multiple on-line spectroscopic analysis (UV, IR, 1H-NMR and MS).

1 reference

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7 January 2021

Flow injection spectroscopic analysis of model drugs using on-line UV-diode array, FT-infrared and 1H-nuclear magnetic resonance spectroscopy and time-of-flight mass spectrometry

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7 January 2021

Automated analysis of proton NMR spectra from combinatorial rapid parallel synthesis using self-organizing maps

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7 January 2021

N-Arylation of Sulfonamides on Solid Supports

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7 January 2021

Shape-selective recognition of a model Okazaki fragment by geometrically-constrained bis-distamycins

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7 January 2021

Screening of compound libraries for protein binding using flow-injection nuclear magnetic resonance spectroscopy.

1 reference

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7 January 2021

NMR of biofluids and pattern recognition: assessing the impact of NMR parameters on the principal component analysis of urine from rat and mouse

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7 January 2021

Effects of the amount and intensity of exercise on plasma lipoproteins

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7 January 2021

Determination of tacrine metabolites in microsomal incubate by high performance liquid chromatography-nuclear magnetic resonance/mass spectrometry with a column trapping system

1 reference

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7 January 2021

Small volume flow probe for automated direct-injection NMR analysis: design and performance

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7 January 2021

Union of capillary high-performance liquid chromatography and microcoil nuclear magnetic resonance spectroscopy applied to the separation and identification of terpenoids

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7 January 2021

Sample concentration and separation for nanoliter-volume NMR spectroscopy using capillary isotachophoresis

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7 January 2021

Capillary isotachophoresis/NMR: extension to trace impurity analysis and improved instrumental coupling

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7 January 2021

High-throughput method for the production and analysis of large natural product libraries for drug discovery

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7 January 2021

1H NMR Characterization of the Product from Single Solid-Phase Resin Beads Using Capillary NMR Flow Probes

1 reference

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7 January 2021

Application of high-field NMR and cryogenic probe technologies in the structural elucidation of poecillastrin a, a new antitumor macrolide lactam from the sponge poecillastra species

1 reference

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7 January 2021

Cryogenic Probe13C NMR Spectroscopy of Urine for Metabonomic Studies

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7 January 2021

NMR difference probe: a dual-coil probe for NMR difference spectroscopy

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7 January 2021

A probe design for the acquisition of homonuclear, heteronuclear, and inverse detected NMR spectra from multiple samples

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7 January 2021

Analysis of multiple samples using multiplex sample NMR: selective excitation and chemical shift imaging approaches

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7 January 2021

Application of Chemical Shift Imaging for Simultaneous and Fast Acquisition of NMR Spectra on Multiple Samples

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7 January 2021

Characterization of small combinatorial chemistry libraries by (1)H NMR. Quantitation with a convenient and novel internal standard

1 reference

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7 January 2021

2,5-Dimethylfuran (DMFu): An Internal Standard for the “Traceless” Quantitation of Unknown Samples via1H NMR†

1 reference

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7 January 2021

Application of a new expert system for the structure elucidation of natural products from their 1D and 2D NMR data

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7 January 2021

Prediction of 1H NMR Chemical Shifts Using Neural Networks

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7 January 2021

The multidimensional filter diagonalization method

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7 January 2021

Solid-phase extraction NMR studies of chromatographic fractions of saponins from Quillaja saponaria

1 reference

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7 January 2021

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1 reference

7 January 2021

Advancing NMR sensitivity for LC-NMR-MS using a cryoflow probe: application to the analysis of acetaminophen metabolites in urine

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7 January 2021

10.1016/S1367-5931(03)00051-6

Identifiers

DOI

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6 August 2017

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PubMed ID

12826127