Effects of the NK1 antagonist, aprepitant, on response to oral and intranasal oxycodone in prescription opioid abusers (Q35162929)

6 August 2017

Effects of the NK1 antagonist, aprepitant, on response to oral and intranasal oxycodone in prescription opioid abusers (English)

1 reference

6 August 2017

1 reference

ChEBI release 2020-05-28

Markus Heilig

2

0 references

author name string

Sharon L Walsh

1

1 reference

6 August 2017

Paul A Nuzzo

3

1 reference

6 August 2017

Pam Henderson

4

1 reference

6 August 2017

Michelle R Lofwall

5

1 reference

6 August 2017

19 January 2012

1 reference

6 August 2017

1 reference

6 August 2017

18

1 reference

6 August 2017

2

1 reference

6 August 2017

332-343

1 reference

Pharmacokinetics of intranasal crushed OxyContin and intravenous oxycodone in nondependent prescription opioid abusers

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Neurokinin-1 receptor antagonists: a comprehensive patent survey

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Agonist-like pharmacotherapy for stimulant dependence: preclinical, human laboratory, and clinical studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

The relative abuse liability of oral oxycodone, hydrocodone and hydromorphone assessed in prescription opioid abusers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Neurokinin 1 receptor antagonism as a possible therapy for alcoholism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

New approaches to chemotherapy-induced nausea and vomiting: from neuropharmacology to clinical investigations

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

An unidentified depressor substance in certain tissue extracts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

The role of substance P in stress and anxiety responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Pharmacotherapy for nicotine dependence

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

The spinal basis of opioid tolerance and physical dependence: Involvement of calcitonin gene-related peptide, substance P, and arachidonic acid-derived metabolites

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Substance P receptor antagonists in psychiatry: rationale for development and therapeutic potential

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Aprepitant: a review of its use in the prevention of chemotherapy-induced nausea and vomiting

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Heterodimerization of substance P and mu-opioid receptors regulates receptor trafficking and resensitization.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Methods for evaluating addiction liability. (A) "Attitude" of opiate addicts toward opiate-like drugs. (B) a short-term "direct" addiction test.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

An Inventory for Measuring Depression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Imaging substance P receptors (NK1) in the living human brain using positron emission tomography.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Seven-transmembrane receptors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Substance P, opioid, and catecholamine systems in the mouse central nervous system (CNS).

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

A substance P-opioid chimeric peptide as a unique nontolerance-forming analgesic

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Distinct mechanism for antidepressant activity by blockade of central substance P receptors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Altered nociception, analgesia and aggression in mice lacking the receptor for substance P

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

RP 67580, a selective antagonist of neurokinin-1 receptors, modifies some of the naloxone-precipitated morphine withdrawal signs in rats

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

An analysis of drug-seeking behavior in animals

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

The pharmacology of cocaine related to its abuse

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Substance P in the human brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Naloxone blocks conditioned place preference induced by substance P and [pGlu6]-SP(6–11)

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Positively reinforcing effects of the neurokinin substance P in the basal forebrain: mediation by its C-terminal sequence

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

The Fifth Edition of the Addiction Severity Index

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.

13 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Effects of aprepitant on cytochrome P450 3A4 activity using midazolam as a probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Rewarding effects of opiates are absent in mice lacking the receptor for substance P.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Population pharmacokinetics of aprepitant and dexamethasone in the prevention of chemotherapy-induced nausea and vomiting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Distribution of substance P-like immunoreactive structures in the brainstem of the adult human brain: an immunocytochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1369-1600.2011.00419.X

Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

mu-Opioid receptors often colocalize with the substance P receptor (NK1) in the trigeminal dorsal horn.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354863

Comparative evaluation of morphine, pentazocine and ciramadol in postaddicts

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22260216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22260216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1369-1600.2011.00419.X

1 reference

release_cxels6oer5gujbx7x2r5foijoa

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cxels6oer5gujbx7x2r5foijoa

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

4354863

1 reference

6 August 2017

1 reference