Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes. (Q35168115)

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8 February 2020

title

Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes (English)

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8 February 2020

1

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Rhett P. Ketterling

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8 February 2020

author name string

Jessemy D Neiger

2

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8 February 2020

Julie C Porcher

3

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J Jonathan Keats

4

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8 February 2020

P Leif Bergsagel

5

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8 February 2020

Thomas R Dennis

6

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8 February 2020

Ryan A Knudson

7

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8 February 2020

Robert B Jenkins

8

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Rafael Santana-Davila

9

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Rajiv Kumar

10

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8 February 2020

language of work or name

English

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publication date

22 September 2009

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8 February 2020

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8 February 2020

volume

69

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issue

19

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8 February 2020

page(s)

7518-7523

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The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Thrombopoietin regulates IEX-1 gene expression through ERK-induced AML1 phosphorylation.

28 July 2018

1 reference

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Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome

28 July 2018

1 reference

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A novel vitamin D-regulated immediate-early gene, IEX-1, alters cellular growth and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Roles of the stress-induced gene IEX-1 in regulation of cell death and oncogenesis

28 July 2018

1 reference

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Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice

28 July 2018

1 reference

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Expression of an immediate early gene, IEX-1, in human tissues.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

International scoring system for evaluating prognosis in myelodysplastic syndromes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Differential gene expression of bone marrow-derived CD34+ cells is associated with survival of patients suffering from myelodysplastic syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Conversion Technology for the separation of maternal and paternal copies of any autosomal chromosome in somatic cell hybrids.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Distinct domains for anti- and pro-apoptotic activities of IEX-1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Elevated blood pressure and cardiac hypertrophy after ablation of the gly96/IEX-1 gene

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Immediate early gene X-1 (IEX-1), a hydroxytamoxifen regulated gene with increased stimulation in MCF-7 derived resistant breast cancer cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Divergent regulation of the growth-promoting gene IEX-1 by the p53 tumor suppressor and Sp1

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Identification and characterization of a radiation-inducible glycosylated human early-response gene.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3157243

Synergistic and opposing regulation of the stress-responsive gene IEX-1 by p53, c-Myc, and multiple NF-kappaB/rel complexes

27 September 2018

1 reference

12 December 2020

Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow

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12 December 2020

Development of T-cell lymphomas in Emu-IEX-1 mice

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12 December 2020

Prognostic significance of the immediate early response gene X-1 (IEX-1) expression in pancreatic cancer

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12 December 2020

10.1158/0008-5472.CAN-09-1428

Identifiers

DOI

1 reference

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8 February 2020

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8 February 2020

PubMed publication ID

19773435

1 reference