The vasculopathy of Raynaud's phenomenon and scleroderma (Q35169051)

6 August 2017

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title

The vasculopathy of Raynaud's phenomenon and scleroderma (English)

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6 August 2017

Nicholas A Flavahan

1

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6 August 2017

Sheila Flavahan

series ordinal

2

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6 August 2017

Srabani Mitra

series ordinal

3

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6 August 2017

Maqsood A Chotani

series ordinal

4

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6 August 2017

publication date

1 May 2003

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Rheumatic Diseases Clinics of North America

6 August 2017

published in

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6 August 2017

volume

29

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6 August 2017

issue

2

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6 August 2017

page(s)

275-91, vi

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Systemic sclerosis 'state of the art' 1995

6 August 2017

cites work

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Raynaud's phenomenon and scleroderma. Dysregulated neuroendothelial control of vascular tone

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Physiological significance of alpha(2)-adrenergic receptor subtype diversity: one receptor is not enough

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7 January 2021

Central hypotensive effects of the alpha2a-adrenergic receptor subtype

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7 January 2021

Cardiovascular regulation in mice lacking alpha2-adrenergic receptor subtypes b and c.

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7 January 2021

Cell-type specific targeting of the alpha 2c-adrenoceptor. Evidence for the organization of receptor microdomains during neuronal differentiation of PC12 cells

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7 January 2021

Stimulation frequency-noradrenaline release relationships examined in alpha2A-, alpha2B- and alpha2C-adrenoceptor-deficient mice

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7 January 2021

Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission

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7 January 2021

Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries

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7 January 2021

Cooling evokes redistribution of alpha2C-adrenoceptors from Golgi to plasma membrane in transfected human embryonic kidney 293 cells.

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7 January 2021

Blockade of Vasospastic Attacks by α 2 -Adrenergic but Not α 1 -Adrenergic Antagonists in Idiopathic Raynaud’s Disease

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7 January 2021

Gender difference in levels of alpha2-adrenoceptor mRNA in the rat tail artery

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7 January 2021

Adrenoceptors on blood cells from patients with primary Raynaud's phenomenon

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7 January 2021

Platelets in nonresponders to epinephrine stimulation showed reduced response to ADP.

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7 January 2021

Increased alpha-adrenergic responsiveness in idiopathic Raynaud's disease

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7 January 2021

Cold-induced potentiation of alpha 2-adrenergic vasoconstriction in primary Raynaud's disease

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7 January 2021

Ligand efficacy and potency at recombinant alpha2 adrenergic receptors: agonist-mediated [35S]GTPgammaS binding

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7 January 2021

Venodilation in Raynaud's disease

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7 January 2021

Response of digital arteries to endothelium dependent and independent vasodilators in patients with Raynaud's phenomenon

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7 January 2021

Serum endothelin-1 concentrations and cold provocation in primary Raynaud's phenomenon

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7 January 2021

Calcitonin gene-related peptide and Raynaud's phenomenon

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7 January 2021

Functional studies in small arteries do not support a primary role for endothelin in the pathogenesis of Raynaud's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Digital vascular responses and serum endothelin-1 concentrations in primary and secondary Raynaud's phenomenon

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Non-invasive assessment of vascular reactivity in forearm skin of patients with primary Raynaud's phenomenon and systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Increased alpha2-adrenergic constriction of isolated arterioles in diffuse scleroderma

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7 January 2021

Vascular function in systemic sclerosis.

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7 January 2021

Vascular abnormalities in scleroderma

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7 January 2021

Endothelin, an endothelial-dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endothelial nitric oxide synthase (Glu298Asp) in patients with systemic sclerosis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Beauty and the beast. The nitric oxide paradox in systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

The binding of some human antiendothelial cell antibodies induces endothelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Systemic sclerosis immunoglobulin G autoantibodies bind the human cytomegalovirus late protein UL94 and induce apoptosis in human endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Targeting mediators of vascular injury in scleroderma

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Tumor angiogenesis: therapeutic implications

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7 January 2021

Angiogenesis in progressive systemic sclerosis

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7 January 2021

Vascular endothelial growth factor in patients with rheumatoid arthritis

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7 January 2021

Serum concentrations of vascular endothelial growth factor in collagen diseases

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7 January 2021

Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis

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7 January 2021

Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers

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7 January 2021

Increased concentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis

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7 January 2021

Deficient Smad7 expression: a putative molecular defect in scleroderma

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7 January 2021

Systemic sclerosis stimulates angiogenesis in the chick embryo chorioallantoic membrane.

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7 January 2021

The cell biology of thrombospondin-1.

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7 January 2021

The functions of thrombospondin-1 and-2.

1 reference

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7 January 2021

The pathogenesis of atherosclerosis--an update

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7 January 2021

Atherosclerosis — An Inflammatory Disease

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7 January 2021

Smooth muscle cell heterogeneity in pulmonary and systemic vessels. Importance in vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Smooth muscle cell origin and its relation to heterogeneity in development and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Molecular control of vascular smooth muscle cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Molecular mechanisms of coronary collateral vessel growth

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Fas-mediated apoptosis in accelerated graft arteriosclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Differentiated vascular myocytes: are they involved in neointimal formation?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Adventitial fibroblasts: defining a role in vessel wall remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Vascular remodeling and altered protein expression during growth of coronary collateral arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Molecular mechanisms in intimal hyperplasia

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

The extracellular matrix can regulate vascular cell migration, proliferation, and survival: relationships to vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Endothelial Cell Signaling and Endothelial Dysfunction

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Mechanical strain increases smooth muscle and decreases nonmuscle myosin expression in rat vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Extracellular matrix remodeling: multiple paradigms in vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Development and disease in proteinase-deficient mice: role of the plasminogen, matrix metalloproteinase and coagulation system

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

New tricks for old dogs: nonthrombotic effects of thrombin in vessel wall biology

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Elafin, a serine elastase inhibitor, attenuates post-cardiac transplant coronary arteriopathy and reduces myocardial necrosis in rabbits afer heterotopic cardiac transplantation

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Elastin is an essential determinant of arterial morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin-C, and smooth muscle cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Increased elastin-degrading activity and neointimal formation in porcine aortic organ culture. Reduction of both features with a serine proteinase inhibitor

1 reference

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7 January 2021

Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome

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7 January 2021

Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Murine animal models of systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

The genetics of systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Association of fibrillin 1 single-nucleotide polymorphism haplotypes with systemic sclerosis in Choctaw and Japanese populations

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Abnormalities in fibrillin 1-containing microfibrils in dermal fibroblast cultures from patients with systemic sclerosis (scleroderma)

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Mouse models of genetic diseases resulting from mutations in elastic fiber proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Cytokine directed therapy in scleroderma: rationale, current status, and the future

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Apoptosis and myofibroblasts in the pathogenesis of systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Role of apoptosis and transforming growth factor beta1 in fibroblast selection and activation in systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Peripheral blood fibrocytes: mesenchymal precursor cells and the pathogenesis of fibrosis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Microchimerism and scleroderma

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

New perspectives on the etiology of systemic sclerosis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Microchimerism and autoimmune disease

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Scleroderma autoantigens are uniquely fragmented by metal-catalyzed oxidation reactions: implications for pathogenesis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Cell surface thrombospondin is functionally essential for vascular smooth muscle cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

A CD36 synthetic peptide inhibits bleomycin-induced pulmonary inflammation and connective tissue synthesis in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Human allograft acceptance is associated with immune regulation

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Vascular smooth muscle cells of recipient origin mediate intimal expansion after aortic allotransplantation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Recipient origin of neointimal vascular smooth muscle cells in cardiac allografts with transplant arteriosclerosis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Origin of neointimal endothelium and alpha-actin-positive smooth muscle cells in transplant arteriosclerosis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

Circulating smooth muscle progenitor cells contribute to atherosclerosis

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https://api.crossref.org/works/10.1016%2FS0889-857X%2803%2900021-8

7 January 2021

10.1016/S0889-857X(03)00021-8

Identifiers

DOI

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6 August 2017

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