Multiple biochemical activities of NM23/NDP kinase in gene regulation (Q35171602)

6 August 2017

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title

Multiple biochemical activities of NM23/NDP kinase in gene regulation (English)

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6 August 2017

Edith H Postel

1

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6 August 2017

1 February 2003

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Journal of Bioenergetics and Biomembranes

6 August 2017

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6 August 2017

35

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6 August 2017

1

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6 August 2017

31-40

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https://scigraph.springernature.com/pub.10.1023/a:1023485505621

6 August 2017

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Escherichia coli strains (ndk) lacking nucleoside diphosphate kinase are powerful mutators for base substitutions and frameshifts in mismatch-repair-deficient strains

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Mismatch repair and cancer

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Catalysis of DNA cleavage and nucleoside triphosphate synthesis by NM23-H2/NDP kinase share an active site that implies a DNA repair function

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Cancer cells exhibit a mutator phenotype

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X-ray structure of human nucleoside diphosphate kinase B complexed with GDP at 2 A resolution

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NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter

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Base excision repair of DNA in mammalian cells

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Nucleoside diphosphate kinase enzyme activity of NM23-H2/PuF is not required for its DNA binding and in vitro transcriptional functions

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MutS preferentially recognizes cisplatin- over oxaliplatin-modified DNA.

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BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells.

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A nuclease hypersensitive element in the human c-myc promoter adopts several distinct i-tetraplex structures

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Three-dimensional structure of nucleoside diphosphate kinase

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12 December 2020

Cleavage of DNA by human NM23-H2/nucleoside diphosphate kinase involves formation of a covalent protein-DNA complex

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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Human NM23/nucleoside diphosphate kinase regulates gene expression through DNA binding to nuclease-hypersensitive transcriptional elements

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Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element

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12 December 2020

Gene expression profiles in normal and cancer cells

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Nm23/nucleoside diphosphate kinase in human cancers

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Initiation of base excision repair: glycosylase mechanisms and structures

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Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity

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12 December 2020

Identifiers

DOI

10.1023/A:1023485505621

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PubMed ID

12848339

Dimensions Publication ID

6 August 2017

0 references

1 reference

PubMed ID

12848339