HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development (Q35172770)

6 August 2017

title

HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development (English)

1 reference

6 August 2017

2

Garnett Kelsoe

1 reference

6 August 2017

3

Barton F Haynes

1 reference

6 August 2017

1

Laurent Verkoczy

1 reference

6 August 2017

publication date

22 May 2014

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6 August 2017

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6 August 2017

volume

10

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6 August 2017

issue

5

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6 August 2017

page(s)

e1004073

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Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

22 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10

28 July 2018

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B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates

28 July 2018

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28 July 2018

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Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10

28 July 2018

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

28 July 2018

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28 July 2018

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28 July 2018

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Anti-HIV B Cell lines as candidate vaccine biosensors

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Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

28 July 2018

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Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation

28 July 2018

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Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls

28 July 2018

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28 July 2018

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Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

28 July 2018

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HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

21 January 2018

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Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies

21 January 2018

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Checkpoints in lymphocyte development and autoimmune disease

21 January 2018

1 reference

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Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004073

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004073

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004073

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

21 January 2018

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Structural vaccinology starts to deliver

27 September 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004073

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004073

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004073

10.1371/JOURNAL.PPAT.1004073

21 January 2018

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DOI

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6 August 2017

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6 August 2017

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