Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4. (Q35173275)

6 August 2017

Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4. (English)

1 reference

6 August 2017

7

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5 June 2020

author name string

Shawna Guillemette

1

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5 June 2020

Ryan W Serra

2

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5 June 2020

Min Peng

3

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5 June 2020

Janelle A Hayes

4

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5 June 2020

Panagiotis A Konstantinopoulos

5

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5 June 2020

Michael R Green

6

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5 June 2020

publication date

1 March 2015

1 reference

6 August 2017

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5 June 2020

volume

29

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5 June 2020

issue

5

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5 June 2020

page(s)

489-494

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Synthetic lethality and cancer therapy: lessons learned from the development of PARP inhibitors

5 June 2020

cites work

1 reference

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Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

CHD chromatin remodelling enzymes and the DNA damage response.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

13 July 2018

1 reference

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Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

13 July 2018

1 reference

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

13 July 2018

1 reference

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Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment.

13 July 2018

1 reference

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Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin

13 July 2018

1 reference

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Integrated genomic analyses of ovarian carcinoma

13 July 2018

1 reference

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Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.

13 July 2018

1 reference

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Error-prone translesion synthesis mediates acquired chemoresistance

13 July 2018

1 reference

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Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy

13 July 2018

1 reference

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The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage

13 July 2018

1 reference

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The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage

13 July 2018

1 reference

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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

13 July 2018

1 reference

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The Mi-2/NuRD complex: a critical epigenetic regulator of hematopoietic development, differentiation and cancer.

13 July 2018

1 reference

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Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma

13 July 2018

1 reference

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REV3L confers chemoresistance to cisplatin in human gliomas: the potential of its RNAi for synergistic therapy

13 July 2018

1 reference

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Resistance to therapy caused by intragenic deletion in BRCA2

13 July 2018

1 reference

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Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

13 July 2018

1 reference

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An elaborate pathway required for Ras-mediated epigenetic silencing

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

The human Mi-2/NuRD complex and gene regulation

13 July 2018

1 reference

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Translesion synthesis: Y-family polymerases and the polymerase switch

13 July 2018

1 reference

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Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations

13 July 2018

1 reference

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Biallelic inactivation of BRCA2 in Fanconi anemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4358401

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

13 July 2018

1 reference

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13 July 2018

Identifiers

DOI

10.1101/GAD.256214.114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25737278%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

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5 June 2020

1 reference

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