Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium (Q35179335)

7 August 2017

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title

Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium (English)

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7 August 2017

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Michelle A Vincent

1

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PubMed ID

12866989

7 August 2017

Monica Montagnani

series ordinal

2

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PubMed ID

12866989

7 August 2017

Michael J Quon

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3

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7 August 2017

1 August 2003

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7 August 2017

Current diabetes report

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7 August 2017

3

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7 August 2017

279-288

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7 August 2017

4

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https://scigraph.springernature.com/pub.10.1007/s11892-003-0018-9

7 August 2017

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cites work

Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells

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Insulin stimulates both endothelin and nitric oxide activity in the human forearm.

21 January 2018

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Effects of sympathectomy and nitric oxide synthase inhibition on vascular actions of insulin in humans.

21 January 2018

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Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11892-003-0018-9

Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase

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Blood flow and muscle metabolism: a focus on insulin action.

21 January 2018

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Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

21 January 2018

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Hemodynamic actions of insulin

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Endothelin contributes to basal vascular tone and endothelial dysfunction in human obesity and type 2 diabetes.

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Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells

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Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

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Reversible insulin resistance in non-insulin-dependent diabetes mellitus

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Nitric oxide release accounts for insulin's vascular effects in humans

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Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans

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Improved endothelial function with metformin in type 2 diabetes mellitus

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Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance.

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Skeletal muscle microvascular recruitment by physiological hyperinsulinemia precedes increases in total blood flow

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Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cells

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Effect of flow rate and glucose concentration on glucose uptake rate by the rat limb

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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

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Physiologic hyperinsulinemia enhances human skeletal muscle perfusion by capillary recruitment

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Exercise training improves insulin-mediated capillary recruitment in association with glucose uptake in rat hindlimb

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Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells

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Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin

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Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1.

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Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

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The IRS-signaling system: a network of docking proteins that mediate insulin and cytokine action

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Effect of perfusion rate on the time course of insulin-mediated skeletal muscle glucose uptake

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12 December 2020

Effect of exogenous insulin on blood pressure regulation in healthy and diabetic subjects.

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Active Rho kinase (ROK-alpha ) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells.

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12 December 2020

Effects of overexpressing wild-type and mutant PDGF receptors on translocation of GLUT4 in transfected rat adipose cells

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12 December 2020

Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus

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12 December 2020

Imidapril, an angiotensin-converting enzyme inhibitor, improves insulin sensitivity by enhancing signal transduction via insulin receptor substrate proteins and improving vascular resistance in the Zucker fatty rat.

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12 December 2020

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Mechanisms of enhanced insulin sensitivity in endurance-trained athletes: effects on blood flow and differential expression of GLUT 4 in skeletal muscles

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12 December 2020

Insulin-mediated hemodynamic changes are impaired in muscle of Zucker obese rats

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12 December 2020

Inhibition of phosphatidylinositol 3-kinase enhances mitogenic actions of insulin in endothelial cells

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12 December 2020

Vascular recruitment in skeletal muscle during exercise and hyperinsulinemia assessed by contrast ultrasound

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12 December 2020

Dilation of isolated skeletal muscle arterioles by insulin is endothelium dependent and nitric oxide mediated

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12 December 2020

Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose uptake in vivo

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12 December 2020

Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex.

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12 December 2020

PPARgamma and atherosclerosis: effects on cell growth and movement

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12 December 2020

Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway.

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12 December 2020

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

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12 December 2020

Endothelial dysfunction precedes hypertension in diet-induced insulin resistance.

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12 December 2020

Troglitazone, an insulin sensitizer, increases forearm blood flow in humans

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12 December 2020

10.1007/S11892-003-0018-9

Identifiers

DOI

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7 August 2017

1 reference

PubMed ID

12866989