Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay (Q35182910)

7 August 2017

title

Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay (English)

1 reference

7 August 2017

Yvette Schollmeier

1

1 reference

7 August 2017

Jean Michel Krause

2

1 reference

7 August 2017

Susanne Kreye

3

1 reference

7 August 2017

Jörg Malsam

4

1 reference

7 August 2017

Thomas H Söllner

5

1 reference

7 August 2017

language of work or name

English

0 references

publication date

5 July 2011

1 reference

Journal of Biological Chemistry

7 August 2017

published in

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7 August 2017

volume

286

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7 August 2017

issue

35

1 reference

7 August 2017

page(s)

30582-30590

1 reference

describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3162418/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1 as a key regulator of neurosecretion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Membrane fusion: five lipids, four SNAREs, three chaperones, two nucleotides, and a Rab, all dancing in a ring on yeast vacuoles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

One SNARE complex is sufficient for membrane fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Autoinhibition of SNARE complex assembly by a conformational switch represents a conserved feature of syntaxins.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Abrogating Munc18-1-SNARE complex interaction has limited impact on exocytosis in PC12 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

The carboxy-terminal domain of complexin I stimulates liposome fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Membrane fusion: grappling with SNARE and SM proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

A role for the syntaxin N-terminus.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18a scaffolds SNARE assembly to promote membrane fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Interplay between lipids and the proteinaceous membrane fusion machinery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

The fusion pores of Ca2+ -triggered exocytosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1 prevents the formation of ectopic SNARE complexes in living cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1 in secretion: lonely Munc joins SNARE team and takes control.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

SNARE proteins and 'membrane rafts'.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Mechanism of arachidonic acid action on syntaxin-Munc18.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1 binds directly to the neuronal SNARE complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Functionally and spatially distinct modes of munc18-syntaxin 1 interaction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Selective activation of cognate SNAREpins by Sec1/Munc18 proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

SNAREs--engines for membrane fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Molecular dissection of the Munc18c/syntaxin4 interaction: implications for regulation of membrane trafficking.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

The Sec1p/Munc18 protein Vps45p binds its cognate SNARE proteins via two distinct modes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1 stabilizes syntaxin 1, but is not essential for syntaxin 1 targeting and SNARE complex formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Principles of exocytosis and membrane fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Defects in synaptic vesicle docking in unc-18 mutants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Fusion of cells by flipped SNAREs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Snares and Munc18 in synaptic vesicle fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc18-1 promotes large dense-core vesicle docking

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Three SNARE complexes cooperate to mediate membrane fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Compartmental specificity of cellular membrane fusion encoded in SNARE proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

nSec1 binds a closed conformation of syntaxin1A.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Sec1p binds to SNARE complexes and concentrates at sites of secretion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

SNAREpins: minimal machinery for membrane fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

SNAP receptors implicated in vesicle targeting and fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Use of resonance energy transfer to monitor membrane fusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Membrane fusion: SNAREs and regulation

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Synaptic assembly of the brain in the absence of neurotransmitter secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

A conformational switch in syntaxin during exocytosis: role of munc18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

The synaptic vesicle cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

UNC-13 is required for synaptic vesicle fusion in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Munc18/Syntaxin interaction kinetics control secretory vesicle dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Molecular anatomy of a trafficking organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Anatomy and dynamics of a supramolecular membrane protein cluster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Syntaxin 1A is delivered to the apical and basolateral domains of epithelial cells: the role of munc-18 proteins.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3162418

Synaptotagmin-1 Docks Secretory Vesicles to Syntaxin-1/SNAP-25 Acceptor Complexes

27 September 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.269886

Regulation of the UNC-18-Caenorhabditis elegans syntaxin complex by UNC-13

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21730064

12 December 2020

inferred from PubMed ID database lookup

N- to C-Terminal SNARE Complex Assembly Promotes Rapid Membrane Fusion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21730064

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/21730064

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M111.269886

1 reference

7 August 2017

1 reference

7 August 2017

1 reference