Cell death, Bcl-2, Bax, and the cerebellum (Q35184501)

7 August 2017

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title

Cell death, Bcl-2, Bax, and the cerebellum (English)

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7 August 2017

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Michael W Vogel

1

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7 August 2017

publication date

1 December 2002

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7 August 2017

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7 August 2017

volume

1

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7 August 2017

issue

4

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7 August 2017

page(s)

277-287

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Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo

7 August 2017

cites work

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12 December 2020

Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene

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12 December 2020

Process of differentiation of cerebellar Purkinje neurons in the chick embryo

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12 December 2020

Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.

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12 December 2020

Life-or-death decisions by the Bcl-2 protein family.

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12 December 2020

Bax promotes neuronal cell death and is downregulated during the development of the nervous system.

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12 December 2020

Neurodegeneration in Lurcher mice occurs via multiple cell death pathways

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12 December 2020

Overexpression of a Hu-bcl-2 transgene in Lurcher mutant mice delays Purkinje cell death.

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12 December 2020

Susceptibility of cerebellar granule neurons derived from Bcl-2-deficient and transgenic mice to cell death

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12 December 2020

Developmental changes in expression and distribution of the glutamate receptor channel delta 2 subunit according to the Purkinje cell maturation.

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12 December 2020

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

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12 December 2020

Mitochondria as the central control point of apoptosis

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12 December 2020

Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

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12 December 2020

Developmental studies of the inferior olivary nucleus in staggerer mutant mice.

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12 December 2020

Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

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12 December 2020

Identification and mapping of a mouse gene influencing cerebellar folial pattern.

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12 December 2020

Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease

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12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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12 December 2020

The induction of multiple cell cycle events precedes target-related neuronal death.

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12 December 2020

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12 December 2020

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

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12 December 2020

In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum

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12 December 2020

Expression of bcl-2, bax, and caspase-3 in the brain of the developing rat.

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12 December 2020

Increased cerebellar Purkinje cell numbers in mice overexpressing a human bcl-2 transgene.

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12 December 2020

Caspases: enemies within

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12 December 2020

Spatial and temporal changes in natural and target deprivation-induced cell death in the mouse inferior olive.

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12 December 2020

Further evidence that a mouse chromosome 4 locus influences cerebellar folial pattern

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12 December 2020

Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice

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12 December 2020

Mechanisms of Neural Patterning and Specification in the Development Cerebellum

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12 December 2020

Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos.

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12 December 2020

Ultrastructural differences during embryonic cell death in normal and peripherally deprived ciliary ganglia

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12 December 2020

Apoptosis. Till death us do part.

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12 December 2020

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

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12 December 2020

Sonic hedgehog regulates the growth and patterning of the cerebellum

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12 December 2020

Postnatal expression of Hu-bcl-2 gene in Lurcher mutant mice fails to rescue Purkinje cells but protects inferior olivary neurons from target-related cell death.

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12 December 2020

Differential glutamatergic innervation in cytochrome oxidase-rich and -poor regions of the macaque striate cortex: quantitative EM analysis of neurons and neuropil

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12 December 2020

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

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12 December 2020

Bax inactivation in lurcher mutants rescues cerebellar granule cells but not purkinje cells or inferior olivary neurons

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12 December 2020

The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

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12 December 2020

The lurcher gene induces apoptotic death in cerebellar Purkinje cells

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12 December 2020

Energetics in the pathogenesis of neurodegenerative diseases

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12 December 2020

GluR delta 2 and the development and death of cerebellar Purkinje neurons in lurcher mice

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12 December 2020

Differences in bcl-2- and bax-independent function in regulating apoptosis in sensory neuron populations

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12 December 2020

Cytochrome oxidase activity is increased in +/Lc Purkinje cells destined to die.

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12 December 2020

Natural loss of Purkinje cells during development and increased loss with alcohol

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12 December 2020

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

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12 December 2020

The development of facial motoneurones in the mouse--neuronal death and the innervation of the facial muscles

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12 December 2020

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

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12 December 2020

Observations on degenerative changes of purkinje cells during early development in mice and in normal and otocyst-deprived chickens

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12 December 2020

Regional variation and absence of large neurons in the cerebellum of the staggerer mouse

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12 December 2020

Development of the brachial lateral motor column in the wingless mutant chick embryo: motoneuron survival under varying degrees of peripheral load

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12 December 2020

An autoradiographic analysis of histogenesis in the mouse cerebellum

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12 December 2020

Development of the lateral motor column in the limbless mutant chick embryo

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12 December 2020

Local control of granule cell generation by cerebellar Purkinje cells

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12 December 2020

Direct correlation between Purkinje and granule cell number in the cerebella of lurcher chimeras and wild-type mice.

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12 December 2020

Strain-specific variations in the folial pattern of the mouse cerebellum

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12 December 2020

Massive loss of mid- and hindbrain neurons during embryonic development of homozygous lurcher mice.

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12 December 2020

Neuronal death and synapse elimination in the olivocerebellar system. I. Cell counts in the inferior olive of developing rats.

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12 December 2020

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice

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12 December 2020

Evidence for large-scale astrocyte death in the developing cerebellum

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12 December 2020

Cell death of motoneurons in the chick embryo spinal cord. I. A light and electron microscopic study of naturally occurring and induced cell loss during development

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12 December 2020

bcl-2 deficiency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine

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12 December 2020

Bcl-2 and Bax function independently to regulate cell death

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12 December 2020

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development

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12 December 2020

Immunolocalization of Bcl-xL/S in the central nervous system of neonatal and adult rats.

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12 December 2020

Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells

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12 December 2020

The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis

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12 December 2020

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

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12 December 2020

Numerical matching between granule and Purkinje cells in lurcher chimeric mice: a hypothesis for the trophic rescue of granule cells from target-related cell death

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12 December 2020

Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2

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12 December 2020

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

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12 December 2020

Cerebellar deficient folia (cdf): a new mutation on mouse chromosome 6

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12 December 2020

Bax, Bid and the permeabilization of the mitochondrial outer membrane in apoptosis

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12 December 2020

The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining

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12 December 2020

bcl-2 transgene expression can protect neurons against developmental and induced cell death

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12 December 2020

Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides.

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12 December 2020

Structural and quantitative studies on the normal C3H and Lurcher mutant mouse

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12 December 2020

Early development of the Lurcher cerebellum: Purkinje cell alterations and impairment of synaptogenesis

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12 December 2020

The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family

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12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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12 December 2020

Apoptotic cell death in the cerebellum of mutant weaver and lurcher mice

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12 December 2020

Function and expression of the Bcl-x gene in the developing and adult nervous system.

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12 December 2020

Numerical matching during cerebellar development: quantitative analysis of granule cell death in staggerer mouse chimeras

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12 December 2020

Bax and p53 are differentially involved in the regulation of caspase-3 expression and activation during neurodegeneration in Lurcher mice

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12 December 2020

Genetic analysis of cerebellar folial pattern in crosses of C57BL/6J and DBA/2J inbred mice

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12 December 2020

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

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12 December 2020

Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice

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12 December 2020

Development and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study

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12 December 2020

Increased inferior olivary neuron and cerebellar granule cell numbers in transgenic mice overexpressing the human Bcl-2 gene.

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12 December 2020

Bcl-2 affects survival but not neuronal differentiation of PC12 cells

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12 December 2020

bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations

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12 December 2020

Genetic control of the mouse cerebellum: identification of quantitative trait loci modulating size and architecture.

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12 December 2020

Numerical matching in the mammalian CNS: lack of a competitive advantage of early over late-generated cerebellar granule cells

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12 December 2020

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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12 December 2020

Immunohistochemical analysis of developmental stage of external granular layer neurons which undergo apoptosis in postnatal rat cerebellum.

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12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

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12 December 2020

Electron microscopic analysis of postnatal histogenesis in the cerebellar cortex of staggerer mutant mice

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12 December 2020

Elimination of Bax expression in mice increases cerebellar purkinje cell numbers but not the number of granule cells

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12 December 2020

Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimeric mice. II. Granule cell death.

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12 December 2020

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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12 December 2020

Postnatal development of the inferior olivary complex in the rat. III. A morphometric analysis of volumetric growth and neuronal cell number.

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12 December 2020

Interaction of granule, Purkinje and inferior olivary neurons in lurcher chimaeric mice. I. Qualitative studies.

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12 December 2020

Microglia and cell death in the developing mouse cerebellum

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12 December 2020

Elevation of resting mitochondrial membrane potential of neural cells by cyclosporin A, BAPTA-AM, and bcl-2.

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12 December 2020

Postnatal development of the cerebellar cortex in the rat. II. Phases in the maturation of Purkinje cells and of the molecular layer

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12 December 2020

BCL-2 family members and the mitochondria in apoptosis

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12 December 2020

Differential expression of bcl-w and bcl-x messenger RNA in the developing and adult rat nervous system

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12 December 2020

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

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12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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12 December 2020

bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS.

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12 December 2020

The Bcl-2 protein family: arbiters of cell survival

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12 December 2020

10.1080/147342202320883588

Identifiers

DOI

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Dimensions Publication ID

7 August 2017

1037847685

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