Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice. (Q35187119)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841315%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice (English)

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10 February 2020

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3

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10 February 2020

author name string

Kimberly M Davis

series ordinal

1

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10 February 2020

Shigeki Nakamura

series ordinal

2

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10 February 2020

language of work or name

English

0 references

publication date

15 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841315%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

10 February 2020

published in

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10 February 2020

volume

121

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10 February 2020

page(s)

3666-3676

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10 February 2020

issue

9

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The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes

10 February 2020

cites work

1 reference

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Modifications to the peptidoglycan backbone help bacteria to establish infection

13 July 2018

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Nod1 and Nod2 regulation of inflammation in the Salmonella colitis model

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Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion

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13 July 2018

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13 July 2018

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The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls

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A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide

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13 July 2018

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Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation

13 July 2018

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Structural variation in the glycan strands of bacterial peptidoglycan

13 July 2018

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Intracellular NOD-like receptors in innate immunity, infection and disease

13 July 2018

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13 July 2018

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Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria

13 July 2018

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A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system

13 July 2018

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13 July 2018

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13 July 2018

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Role for erbin in bacterial activation of Nod2

13 July 2018

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

13 July 2018

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13 July 2018

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

13 July 2018

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

13 July 2018

1 reference

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Peptidoglycan N-acetylglucosamine deacetylase, a putative virulence factor in Streptococcus pneumoniae

13 July 2018

1 reference

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RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

13 July 2018

1 reference

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Involvement of receptor-interacting protein 2 in innate and adaptive immune responses

13 July 2018

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Innate immune recognition

13 July 2018

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Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae

13 July 2018

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The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin

13 July 2018

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

13 July 2018

1 reference

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Transcriptional regulation of the human monocyte chemoattractant protein-1 gene. Cooperation of two NF-kappaB sites and NF-kappaB/Rel subunit specificity.

13 July 2018

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Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia

13 July 2018

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Monocyte chemoattractant protein-1 gene is expressed in activated neutrophils and retinoic acid-induced human myeloid cell lines

13 July 2018

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Specificity of the autolysin of Streptococcus (Diplococcus) pneumoniae

13 July 2018

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Some aspects of the pneumococcal carrier state.

13 July 2018

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Ultrastructural localization of lysozyme in human neutrophils by immunogold

13 July 2018

1 reference

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Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae

13 July 2018

1 reference

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Pneumolysin localizes to the cell wall of Streptococcus pneumoniae.

13 July 2018

1 reference

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Nod2-dependent Th2 polarization of antigen-specific immunity.

27 September 2018

1 reference

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NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity

27 September 2018

1 reference

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Why are pathogenic staphylococci so lysozyme resistant? The peptidoglycan O-acetyltransferase OatA is the major determinant for lysozyme resistance of Staphylococcus aureus

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163965

Mouse Lysozyme M Is Important in Pulmonary Host Defense againstKlebsiella pneumoniaeInfection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163965

Cationic polypeptides are required for antibacterial activity of human airway fluid.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3163965

The immune response to pneumococcal proteins during experimental human carriage

27 September 2018

1 reference

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The pgdA gene encodes for a peptidoglycan N-acetylglucosamine deacetylase in Streptococcus pneumoniae.

27 September 2018

1 reference

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Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae

27 September 2018

1 reference

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Nod1-Mediated Innate Immune Recognition of Peptidoglycan Contributes to the Onset of Adaptive Immunity

27 September 2018

1 reference

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Attenuation of penicillin resistance in a peptidoglycan O-acetyl transferase mutant of Streptococcus pneumoniae

15 November 2018

1 reference

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Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages

15 November 2018

1 reference

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A rapid flow cytometric method for determining the cellular composition of bronchoalveolar lavage fluid cells in mouse models of asthma

15 November 2018

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12 December 2020

Digestion of Streptococcus pneumoniae cell walls with its major peptidoglycan hydrolase releases branched stem peptides carrying proinflammatory activity

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12 December 2020

MCP-1 is selectively expressed in the late phase by cytokine-stimulated human neutrophils: TNF-alpha plays a role in maximal MCP-1 mRNA expression

1 reference

12 December 2020

Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis

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12 December 2020

Ultrastructural immunocytochemical localization of lysozyme in human monocytes and macrophages

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12 December 2020

Induction of Pulmonary Inflammation by Components of the Pneumococcal Cell Surface1–2

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12 December 2020

The contribution of pneumococcal cell wall to the pathogenesis of experimental otitis media

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12 December 2020

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

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12 December 2020

Identifiers

DOI

10.1172/JCI57761

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841315%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21841315%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference